Immune modules shared by innate lymphoid cells and T cells - 09/11/16
Abstract |
In recent years, innate lymphoid cells (ILCs) have emerged as innate correlates to T cells. The similarities between ILCs and T cells indicate that lymphocytes of fundamentally distinct lineages can share core “immune modules” that encompass transcriptional circuitry and effector functions while using nonredundant complementary mechanisms of pattern recognition to enact these functions. We review modules currently recognized to be shared between ILCs and T cells.
Le texte complet de cet article est disponible en PDF.Key words : Innate lymphoid cell, T cell, innate, adaptive, lymphocyte
Abbreviations used : AHR, Eomes, ILC, ILC1, ILC2, ILC3, NFAT, NK, ROR, STAT, T-bet, TCR, TF, TRAIL, Treg
Plan
| Supported by the US National Institutes of Health (R01DE021255 and R21CA16719 to the Colonna laboratory and 1F30DK107053-01 to M.L.R.). |
Vol 138 - N° 5
P. 1243-1251 - novembre 2016 Retour au numéro
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