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A Multisite Study of Family Functioning Impairment in Pediatric Obsessive-Compulsive Disorder - 18/04/17

Doi : 10.1016/j.jaac.2016.12.012 
S. Evelyn Stewart, MD a, , Yu-Pei Hu, MD, MPH b, Aldrich Leung, MD c, Elaine Chan, BSc d, Dianne M. Hezel, MA e, Sarah Yao Lin, MSc f, Laura Belschner, MSc f, Casey Walsh, MSW g, Daniel A. Geller, MBBS, FACP h, David L. Pauls, PhD h
a University of British Columbia (UBC), Vancouver, Canada; British Columbia Children’s Hospital, Vancouver; the Provincial Health Services Administration, British Columbia; Massachusetts General Hospital, Boston; and Harvard University, Boston 
b Duke University Medical Center, Durham, NC 
c UBC 
d University of Alberta, Edmonton, Alberta, Canada 
e Harvard University 
f UBC and the Child and Family Research Institute, Vancouver 
g University of Texas, Austin 
h Massachusetts General Hospital and Harvard University 

Correspondence to S. Evelyn Stewart, MD, University of British Columbia, A3-121, 938 West 28th Avenue, Vancouver, BC, CanadaUniversity of British ColumbiaA3-121, 938 West 28th AvenueVancouverBCCanada

Abstract

Objective

Familial aspects of pediatric obsessive-compulsive disorder (OCD), including accommodation and treatment, have received notable and warranted attention. However, individual perspectives of its repercussions on family functioning, including emotional and occupational parental burden, have not been closely examined. The present study details this topic using a large multicenter sample.

Method

Participants included 354 youth affected with OCD and their mothers and fathers ascertained through OCD programs in Boston, Massachusetts (n = 180) and Vancouver, British Columbia (n = 174). The validated OCD Family Functioning Scale and standard OCD measurements were completed. Descriptive, between-site, and cross-perspective comparative analyses were followed by regression model testing to predict family impairment.

Results

Family functioning was negatively affected from youth, mother, and father perspectives. Impairment was reportedly more extensive at the time of worst OCD severity and was greater from maternal versus paternal viewpoints. Most frequently affected family tasks and implicated OCD symptoms included morning and bedtime routines and intrusive thoughts. Emotional repercussions in all members included stress and anxiety, followed by frustration or anger in youth and sadness in parents. Nearly half of mothers and one third of fathers reported daily occupational impairment. Compared with youth self-report, parents perceived fewer social and academic effects on their child. Family accommodation most consistently predicted family impairment, especially from parent perspectives. OCD and compulsion severity, contamination and religious obsessions, and comorbidities also predicted various perspectives of family subdomain impairment.

Conclusion

This study quantitatively details the pervasive burden that pediatric OCD places on families, as reported from complementary relative perspectives. Further attention to this topic is warranted in clinical and research realms.

Le texte complet de cet article est disponible en PDF.

Key words : obsessive-compulsive disorder, family, parents, emotional, occupational


Plan


 This article is discussed in an editorial by Dr. Eli R. Lebowitz on page 187.
 Clinical guidance is available at the end of this article.
 This work was supported by funding from the Michael Smith Foundation for Health Research and the Canadian Institutes for Health Research awarded to Dr. Stewart and funding from the National Institute of Mental Health awarded to Dr. Pauls.
 Dr. Pauls served as the statistical expert for this research.
 The authors acknowledge the OCD Collaborative Genetics Association Study and the principal investigator, Gerry Nestadt, MBBCh, MPH, from the main Johns Hopkins site in addition to the McLean OCD Institute and all of the families who participated to make this work possible.
 Disclosure: Dr. Stewart serves on the Scientific and Clinical Advisory Board of the International OCD Foundation and served as a Medical Advisory Board Member of the Tourette Association of America from 2012 through 2016. Dr. Geller has received grant or research support from the National Institute of Mental Health, Pfizer, Eli Lilly and Co., GlaxoSmithKline, Otsuka, Forest, Shire, and Neurocrine. He has received honoraria from the American Academy of Child and Adolescent Psychiatry and the Massachusetts General Hospital Psychiatry Academy. He has served on the speakers’ bureau of Eli Lilly and Co. Drs. Hu, Leung, and Pauls and Mss. Chan, Hezel, Lin, Belschner, and Walsh report no biomedical financial interests or potential conflicts of interest.


© 2017  American Academy of Child and Adolescent Psychiatry. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 56 - N° 3

P. 241 - mars 2017 Retour au numéro
Article précédent Article précédent
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