Anatomic mapping and clinicopathologic analysis of benign acral melanocytic neoplasms: A comparison between adults and children - 14/09/17
Abstract |
Background |
The clinicopathologic features of benign acral melanocytic neoplasms (BAMNs) remain poorly understood.
Objective |
To define the clinicopathologic features of BAMNs.
Methods |
We analyzed clinical data and mapped BAMNs anatomically. We also reviewed the histopathologic features of BAMNs and compared these between adults and children.
Results |
We included 396 cases of BAMN: 335 adults and 61 children (376 acquired and 20 congenital lesions). Anatomic mapping revealed that the nonweight-bearing portion of the foot was the most common site in adults (120/335, 35.8%) and the forefoot the most common site in children (17/61, 27.9%) for BAMNs. The long axes of the BAMNs paralleled the dermatoglyphic lines on the palms and soles, as did most tissue sections. The lesion diameters were <5.7 mm in all acquired lesions. Histopathologically, we diagnosed 69 lentigo simplex, 201 junctional, 114 compound, 8 intradermal, and 4 blue nevi. Corneal pigmentation, nests located between rete ridges, dendrite prominence, and cytologic atypia were all significantly more common in children than adults.
Limitations |
The retrospective study design and acquiring patients from a single institution of a single country limited the research results.
Conclusion |
BAMNs develop most commonly on nonweight-bearing regions of the soles in adults and on the forefoot in children. The long axis of the lesion follows the dermatoglyphics, and cytologic atypia is more common in children.
Le texte complet de cet article est disponible en PDF.Key words : adults, anatomic mapping, benign acral melanocytic neoplasms, children, clinical features, cytological atypia, histopathological analysis
Abbreviation used : BAMNs
Plan
| Funding sources: Supported by Chonnam National University Hwasun Hospital Institute for Biomedical Science (grant HCRI 15 016-22). |
|
| Conflicts of interest: None declared. |
Vol 77 - N° 4
P. 735-745 - octobre 2017 Retour au numéro
Article précédent
- Treatment of xanthelasma palpebrarum with a 1064-nm, Q-switched Nd:YAG laser
- Jun Khee Heng, Sze Hon Chua, Chee Leok Goh, Suzanne Cheng, Virlynn Tan, Wee Ping Tan
- Trends in dermatology practices and the implications for the workforce
- Alison Ehrlich, James Kostecki, Helen Olkaba
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?