Increases in hemoglobin concentration and iron needs in response to growth hormone treatment - 07/10/17
Abstract |
We studied 36 children with short stature during the initial 6 months of recombinant human growth hormone treatment and found an elevation in the mean concentration of hemoglobin (p < 0.001). The elevation was highest in the eight patients with bone dysplasia (p < 0.001). The mean concentration of serum ferritin decreased (p < 0.01) and that of serum transferrin increased (p < 0.001). The prevalence of iron deficiency increased from 6 patients (17%) with initial deficiency to 20 (56%) patients after therapy, indicating that iron supplementation should be considered in children treated with recombinant human growth hormone. (J PEDIATR 1994;125:242-5)
Le texte complet de cet article est disponible en PDF.Abbreviations : CI, GH, IGF-I, MCV, rhGH, SDS
Plan
 | From the Children's Hospital, University of Helsinki, Helsinki, Finland |
| Supported by the Foundation for Pediatric Research, Helsinki, Finland. |
 | Reprint requests: Elina Vihervuori, MD, Children's Hospital, University of Helsinki, FIN-00290 Helsinki, Finland. |
| 0022-3476/94/$3.00 + 0 9/22/55718 |
Vol 125 - N° 2
P. 242-245 - août 1994 Retour au numéro
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