New discoveries in the pathogenesis and classification of vitiligo - 14/12/17
on behalf of the
Vitiligo Working Group
Abstract |
Vitiligo is a common autoimmune disease that progressively destroys melanocytes in the skin, resulting in the appearance of patchy depigmentation. This disfiguring condition frequently affects the face and other visible areas of the body, which can be psychologically devastating. The onset of vitiligo often occurs in younger individuals and progresses for life, resulting in a heavy burden of disease and decreased quality of life. Presentation patterns of vitiligo vary, and recognition of these patterns provides both diagnostic and prognostic clues. Recent insights into disease pathogenesis offer a better understanding of the natural history of the disease, its associations, and potential for future treatments. The first article in this continuing medical education series outlines typical and atypical presentations of vitiligo, how they reflect disease activity, prognosis, and response to treatment. Finally, we discuss disease associations, risk factors, and our current understanding of disease pathogenesis.
Le texte complet de cet article est disponible en PDF.Key words : chemical leukoderma, confetti depigmentation, halo nevi, leukoderma, segmental vitiligo, vitiligo, vitiligo pathogenesis
Plan
Supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, under Award Numbers AR061437 and AR069114, and research grants from the Kawaja Vitiligo Research Initiative, Vitiligo Research Foundation, and Dermatology Foundation Stiefel Scholar Award (to Dr Harris). |
|
Conflicts of interest: See above. |
|
Reprints not available from the authors. |
|
Date of release: July 2017 |
|
Expiration date: July 2020 |
Vol 77 - N° 1
P. 1-13 - juillet 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?