Repigmentation through Melanocyte Regeneration in Vitiligo - 15/12/17
, Nathaniel B. Goldstein, BA, MA a, David A. Norris, MD a, bRésumé |
Repigmentation in vitiligo is the process that replaces, in the epidermal basal layer of vitiligo skin, the mature melanocytes that have been killed by cytotoxic T cells specific for melanocyte antigens. It consists of mobilization of melanocyte precursors in the hair follicle bulge and infundibulum to proliferate, migrate, and differentiate into mature melanocytes, moving from the hair follicle bulge to the interfollicular epidermis. The most common clinical presentation of repigmentation in vitiligo is the perifollicular pattern. The most potent stimulus for repigmentation is the UV light.
Le texte complet de cet article est disponible en PDF.Keywords : Vitiligo, Repigmentation, Melanocyte stem cell, Bulge, Hair follicle, Proliferation, Migration, Differentiation
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| Disclosure Statement: The authors do not have any commercial or financial conflicts of interest. |
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| This work was supported by an American Skin Association Research Scholar Award in Vitiligo/Pigment Cell Disorders to Stanca Birlea. |
Vol 35 - N° 2
P. 205-218 - avril 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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