Screening for Clostridium difficile colonization on admission to a hematopoietic stem cell transplant unit may reduce hospital-acquired C difficile infection - 27/03/18
Doi : 10.1016/j.ajic.2017.10.009
Janice Cho, MD a, Maria Teresa Seville, MD b, Sahil Khanna, MBBS c, Darrell S. Pardi, MD c, Priya Sampathkumar, MD d, * 
, Purna C. Kashyap, MBBS c, **
, Purna C. Kashyap, MBBS c, ** a Department of Internal Medicine, Mayo Clinic, Rochester, MN
b Division of Infectious Diseases, Mayo Clinic, Scottsdale, AZ
c Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN
d Division of Infectious Diseases, Mayo Clinic, Rochester, MN
*Address correspondence to Priya Sampathkumar, MD, Division of Infectious Diseases, Mayo Clinic, 200 First St, SW, Rochester, MN 55905. (P. Sampathkumar).Division of Infectious DiseasesMayo Clinic200 First St, SWRochesterMN55905**Address correspondence to Purna Kashyap, MBBS, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St, SW, Rochester, MN 55905. (P. Kashyap).Division of Gastroenterology and HepatologyMayo Clinic200 First St, SWRochesterMN55905
Highlights |
• | Screening for C. difficile at a stem cell transplant unit was implemented. |
• | Patients positive for C. difficile at admission were placed in contact precaution. |
• | Hospital-onset C. difficile infections significantly decreased after instituting screening. |
Abstract |
Clostridium difficile infection rates are higher in patients undergoing hematopoietic stem cell transplants. In our study, patients undergoing hematopoietic stem cell transplants or chemotherapy were screened for C difficile colonization at admission and placed on contact precautions if they were positive. Patient's colonized with C difficile contribute to the overall burden of C difficile infection in hospitals.
Le texte complet de cet article est disponible en PDF.Key Words : Contact precaution, Surveillance, Infection control
Plan
| Preliminary data used for this article were reported in an abstract at Digestive Disease Week 2017, May 6-9, 2017, Chicago, IL. |
|
| Conflicts of interest: None to report. |
|
| JC was involved with study design, data acquisition, analysis, and interpretation of data; drafting of the manuscript; and statistical analysis. MTS was involved with study concept and design, acquisition of data, interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and study supervision. SK was involved with analysis and interpretation of data, critical revision of the manuscript for important intellectual content, and statistical analysis. DP was involved with critical revision of the manuscript for important intellectual content. PS was involved with study concept and design, analysis, and interpretation of data; drafting of the manuscript; critical revision of the manuscript for important intellectual content; and study supervision. PK was involved with study concept and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and study supervision. |
© 2018
Association for Professionals in Infection Control and Epidemiology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 46 - N° 4
P. 459-461 - avril 2018 Retour au numéro
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