Primary Central Nervous System Lymphoma - 01/08/18

Résumé |
Primary central nervous system lymphoma (PCNSL) is an aggressive form of non-Hodgkin lymphoma restricted to the central nervous system. Stereotactic biopsy is the gold-standard for diagnosis of PCNSL. Extent of disease evaluation for newly diagnosed PCNSL patients includes brain imaging, eye examination, cerebrospinal fluid assessment, body imaging, and bone marrow biopsy. Methotrexate-based chemotherapy is the standard induction for PCNSL patients. Optimal consolidation therapy for PCNSL has not been defined, with several options feasible, including chemotherapy, high-dose chemotherapy, and autologous stem cell transplantation or whole-brain radiation therapy. Optimal treatment for relapsed and refractory PCNSL has not been defined.
Le texte complet de cet article est disponible en PDF.Keywords : Primary central nervous system lymphoma, Brain, Non-Hodgkin's lymphoma, Methotrexate
Plan
Vol 36 - N° 3
P. 517-532 - août 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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