Recognizing Hereditary Renal Cancers Through the Microscope : A Pathology Update - 19/11/18
Abstract |
A heightened understanding of hereditary renal cancer syndromes and their molecular basis has led to an increased awareness and recognition of these renal neoplasms by pathologists. Because a diagnosis of hereditary renal cell carcinoma has a profound impact on the patient and family members, when and how to raise such a suspicion via pathologic assessment has become an important yet very challenging task. This review discusses key clinicopathologic, immunohistochemical, and genetic characteristics of hereditary renal cancer syndromes, and important differential diagnostic challenges, emphasizing recent pathologic and molecular advances.
Le texte complet de cet article est disponible en PDF.Keywords : von Hippel-Lindau, Hereditary papillary, Birt-Hogg-Dubé, Hereditary leiomyomatosis renal cell carcinoma, Succinate dehydrogenase, Tuberous sclerosis, Kidney cancer, Familial
Plan
| Disclosure Statement: Dr. Chen was supported by the Society of Memorial Sloan Kettering research grant and NIH/NCI Cancer Center Support Grant P30 CA008748. |
Vol 11 - N° 4
P. 725-737 - décembre 2018 Retour au numéro
Article précédent
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