Restrictive spirometry pattern is associated with low physical activity levels. A population based international study - 21/01/19

Doi : 10.1016/j.rmed.2018.11.017

Anne-Elie Carsin ^a,^b,^c,^d, Elaine Fuertes ^a,^b,^c, Emmanuel Schaffner ^l,^m, Debbie Jarvis ^e,^f, Josep M. Antó ^a,^b,^c,^d, Joachim Heinrich ^g,^h,^ag, Valeria Bellisario ⁱ, Cecilie Svanes ^j,^k, Dirk Keidel ^l,^m, Medea Imboden ^l,^m, Joost Weyler ⁿ, Dennis Nowak ^h, Jesus Martinez-Moratalla ^o, José-Antonio Gullón ^p, José Luis Sanchez Ramos ^q, Seraina Caviezel ^l,^m, Anna Beckmeyer-Borowko ^l,^m, Chantal Raherison ^r, Isabelle Pin ^s, Pascal Demoly ^t, Isa Cerveri ^u, Simone Accordini ^v, Thorarinn Gislason ^w, Kjell Toren ^x, Bertil Forsberg ^y, Christer Janson ^z, Rain Jogi ^aa, Margareta Emtner ^z, Francisco Gómez Real ^ab, Wasif Raza ^y, Bénédicte Leynaert ^ac,^ad, Silvia Pascual ^ae, Stefano Guerra ^a,^af, Shyamali C. Dharmage ^ag, Nicole Probst-Hensch ^l,^m, Judith Garcia-Aymerich ^a,^b,^c,^⁎
^a ISGlobal, Barcelona, Spain
^b Universitat Pompeu Fabra (UPF), Barcelona, Spain
^c CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
^d IMIM (Hospital del Mar Medical Research Institute), Spain
^e MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom
^f Population Health and Occupational Diseases, National Heart and Lung Institute, Imperial College London, London, United Kingdom
^g Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
^h Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Centre Munich, German Centre for Lung Research (DZL), Munich, Germany
ⁱ Department of Public Health and Pediatrics, University of Turin, Turin, Italy
^j Centre for International Health, University of Bergen, Bergen, Norway
^k Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway
^l Swiss Tropical and Public Health Institute, Basel, Switzerland
^m University of Basel, Basel, Switzerland
ⁿ University of Antwerp, Department of Epidemiology and Social Medicine (ESOC), Faculty of Medicine and Health Sciences, Stat UA Statistics Centre, Belgium
^o Complejo Hospitalario Universitario de Albacete, Servicio de Neumología, Universidad de Castilla-La Mancha, Facultad de Medicina, Albacete, Spain
^p Department of Pneumology, Hospital San Agustin, Aviles, Asturias, Spain
^q Department of Nursing, University of Huelva, Huelva, Spain
^r Université de Bordeaux, Inserm, Bordeaux Population Health Research Center, Team EPICENE, UMR 1219, Bordeaux, France
^s CHU de Grenoble Alpes, Department of Pédiatrie, Inserm, U1209, IAB, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Grenoble, France
^t University Hospital of Montpellier, Sorbonne Universités, Montpellier, France
^u Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Matteo Hospital Foundation, University of Pavia, Pavia, Italy
^v Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy
^w Department of Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland
^x Department of Public Health and Community Medicine, Institute of Medicine, Goteburg, Sweden
^y Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
^z Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
^aa Lung Clinic, Tartu University Hospital, Tartu, Estonia
^ab Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway
^ac Inserm, UMR 1152, Pathophysiology and Epidemiology of Respiratory Diseases, Paris, France
^ad University Paris Diderot Paris, UMR 1152, Paris, France
^ae Respiratory Department, Galdakao Hospital, OSI Barrualde-Galdakao, Biscay, Spain
^af Asthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA
^ag Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia

^∗Corresponding author. Barcelona Institute of Global Health (ISGlobal), Doctor Aiguader 88, 08003, Barcelona, Spain.Barcelona Institute of Global Health (ISGlobal)Doctor Aiguader 88Barcelona08003Spain

Abstract

Introduction

Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with normal spirometry.

Methods

Restrictive spirometry pattern was defined as a having post-bronchodilator FEV₁/FVC ≥ Lower Limit of Normal and a FVC<80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physical activity was measured using the International Physical Activity Questionnaire. The odds of having low physical activity (<1st study-specific tertile) was evaluated using adjusted logistic regression models.

Results

Subjects with a restrictive spirometry pattern (n = 280/4721 in ECRHS, n = 143/3570 in SAPALDIA) reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET·min/week in ECRHS, and 3519 vs 3945 MET·min/week in SAPALDIA). Subjects with a restrictive spirometry pattern were more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95%CI 1.07–1.86]) than those with a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levels did not fully explain this finding.

Conclusion

Adults with a restrictive spirometry pattern were more likely to report low levels of physical activity than those with normal spirometry. These results highlight the need to identify and act on this understudied but prevalent condition.

Le texte complet de cet article est disponible en PDF.

Highlights

•	Subjects with a restrictive spirometry pattern had low level of physical activity.
•	Low physical activity was not due to obesity, respiratory symptoms or comorbidities.
•	These results raise awareness about this understudied prevalent condition.

Le texte complet de cet article est disponible en PDF.

Résumé

“Take home” message: This analysis of data from two large population-based studies shows that adults with a restrictive spirometry pattern have low levels of physical activity. This may be one of the reason why higher mortality and morbidity is observed among these subjects.

Le texte complet de cet article est disponible en PDF.

Keywords : Restrictive spirometry pattern, Body mass index, Epidemiology, Lung function, Physical activity

Plan

Introduction

Material and methods

Study design

Lung function measurement

Outcome: physical activity

Body weight and composition

Other relevant covariates

Statistical analysis

Results

Sample characteristics

Overall physical activity levels and by spirometry pattern

Associations between restrictive spirometry pattern and low physical activity

Discussion

Main findings

Implications

Strengths and limitations

Conclusion

Declarations of interest

Funding

Export

Vol 146

P. 116-123 - janvier 2019 Retour au numéro

Article précédent

Utility of fiber-optic bronchoscopy in pulmonary infections among abdominal solid-organ transplant patients: A comprehensive review
Sujit Vijay Sakpal, Steven Donahue, Hector Saucedo Crespo, Christopher Auvenshine, Suresh Kumar Agarwal, Jawad Nazir, Robert N. Santella, Jeffery Steers

| Article suivant

Tracheal collapsibility in adults is dynamic over time
Mette Nygaard, Ole Hilberg, Finn Rasmussen, Elisabeth Bendstrup

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

Déjà abonné à cette revue ?

connectez-vous ou créez un compte

Restrictive spirometry pattern is associated with low physical activity levels. A population based international study - 21/01/19

Abstract

Introduction

Methods

Results

Conclusion

Highlights

Résumé

Plan

Export citations

Fichier

Contenu

Accès rapides

Mon compte

Aide & support

Plateformes Elsevier Masson

Déclaration CNIL