High-risk medication use for Clostridium difficile infection among hospitalized patients with cancer - 31/01/19
, Rose Kohinke, BS b, Phuong Opper, MS b, Samuel F. Hohmann, PhD, MSHSM c, Resa M. Jones, MPH, PhD d, Pramit Nadpara, PhD, MS, BPharm eHighlights |
• | Quinolones were the most common antipseudomonal antibiotics among oncology patients. |
• | Worse Clostridium difficile standardized infection ratio hospitals had the greatest number of oncology days. |
• | The percentage of antibiotics among different oncology services out of total oncology use varied. |
Résumé |
Patients with cancer are vulnerable to Clostridium difficile infection (CDI); hospitals with larger oncology populations may have worse CDI performance. Among 71 academic hospitals studied, there were significant differences in oncology patient-days per 1,000 admissions across CDI standardized infection ratio categories of better, no different, and worse; worse hospitals had the greatest number of patient-days. Oncology patients’ most commonly used high-risk CDI medications were quinolones, third- and fourth-generation cephalosporins, and proton pump inhibitors.
Le texte complet de cet article est disponible en PDF.Key Words : Clostridium difficile, Oncology, Chemotherapeutic agents, Bone marrow transplant
Plan
| Conflicts of interest: None to report. |
Vol 47 - N° 2
P. 217-219 - février 2019 Retour au numéro
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