Flow cytometry: Surface markers and beyond - 07/02/19
, Thomas A. Fleisher, MD bAbstract |
Flow cytometry is a routinely available laboratory method to study cells in suspension from a variety of human sources. Application of this technology as a clinical laboratory method has evolved from the identification of cell-surface proteins to characterizing intracellular proteins and providing multiple different techniques to assess specific features of adaptive and innate immune function. This expanded menu of flow cytometric testing approaches has increased the utility of this platform in characterizing and diagnosing disorders of immune function.
Le texte complet de cet article est disponible en PDF.Key words : Immunophenotype, flow cytometry, primary immunodeficiency, immune function testing
Abbreviations used : CD40L, CD62L, CGD, CTLA4, CVID, DHR, DNT, DOCK8, GFP, HIGM, LAD, LRBA, NK, PID, PMA, RAG, SCID, STAT, TCR, TLR, Vβ, WAS, WASP, XLT
Plan
| Supported by the Division of Intramural Research,National Institute of Allergy and Infectious Diseases, National Institutes of Health. |
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| Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest. |
Vol 143 - N° 2
P. 528-537 - février 2019 Retour au numéro
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