Angioscopic Evaluation During Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension - 12/03/19
, Kuniyoshi Fukai, MD, PhD, Hideo Tsubata, MD, Takehiro Ogata, MD, PhD, Kan Zen, MD, PhD, Takeshi Nakamura, MD, PhD, Tetsuhiro Yamano, MD, PhD, Hirokazu Shiraishi, MD, PhD, Takeshi Shirayama, MD, PhD, Satoaki Matoba, MD, PhDRésumé |
Background |
Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive disorder with a poor prognosis. Recently, balloon pulmonary angioplasty (BPA) has been reported to be an effective treatment for inoperable patients with CTEPH. However, this catheter-based treatment has potentially life-threatening vascular complications. To improve the efficacy and safety of BPA, we assessed the morphological evaluation of organised thrombus and the vascular injury by BPA procedure.
Methods |
In this study, we assessed the morphology of organised thrombi and the vascular injury observed by angioscopy during BPA in 28 lesions from nine CTEPH patients.
Results |
Angioscopy visualised various forms of organised thrombi such as ‘Mesh’, ‘Slit’, ‘Flap’ and ‘Mass’ and allowed for a detailed evaluation of organised thrombus that was difficult to do by conventional contrast angiography. In addition, after balloon dilation for BPA, angioscopy revealed a haemorrhage due to a vessel wall injury caused by wiring and/or ballooning.
Conclusions |
Assessment of organised thrombus and vascular injury by angioscopy might contribute to improving the treatment of the patients with CTEPH.
Le texte complet de cet article est disponible en PDF.Keywords : Chronic thromboembolic pulmonary hypertension, Angioscopy, Balloon pulmonary angioplasty
Plan
Vol 28 - N° 4
P. 655-659 - avril 2019 Retour au numéro
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