Detecting respiratory viruses in children with protracted bacterial bronchitis - 30/04/19
, Chuangli Hao a, Wei Ji a, Yanhong Lu a, Min Wu a, Sainan Chen a, Kun Wang a, Xuejun Shao bAbstract |
Objective |
This study is to investigate the status and clinical significance of respiratory viruses in bronchoalveolar lavage fluid (BALF) of children with PBB.
Methods |
Sixty-eight children with PBB aged from 3 months to 5 years were enrolled and retrospectively reviewed from January 2014 to December 2017. Thirty-five children with persistent pneumonia or chronic pneumonia were matched as controls. Bronchoalveolar lavage fluid samples were collected for respiratory virus detection and bacterial culture.
Results |
The detection rate of bacteria in BALF of children with PBB was 61.8%, which was significantly higher than that of control group (20%) (P < 0.001). The detection rate of virus in BALF of children with PBB was 23.5%, including 6 (8.8%) of rhinovirus, 4 (5.9%) of parainfluenza virus type 3, 2(2.9%) of bocavirus, 2 (2.9%) of respiratory syncytial virus 1 (1.5%) of human metapneumonia virus and 1 (1.5%) of influenza virus A. 10 cases (28.6%) of virus were detected in the control group, including 3 (8.6%) respiratory syncytial virus, 3 (8.6%) rhinovirus and 2 (5.7%) bocavirus. There was no significant difference of viral detection rate between the two groups (P = 0.577).
Conclusion |
Respiratory viruses can be detected in BALF of children with PBB, However, there is no evidence that PBB is virus-induced.
Le texte complet de cet article est disponible en PDF.Highlights |
• | The common symptoms of PBB include wet cough and wheezing. |
• | Positive virus of BALF in patients with PBB were identified in 61.8% of specimens. |
• | No significant difference in viral detection rate between PBB and control groups. |
Keywords : Protracted bacterial bronchitis, Children, Broncho-alveolar lavage, Virus, Bacteria
Plan
Vol 151
P. 55-58 - mai 2019 Retour au numéro
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