The infection preventionists’ (IPs’) presence and intervention in outpatient facilities continues to lag behind the inpatient hospital IPs’ presence. Additionally, in an outpatient world that is heavy on instrument reprocessing, IPs must be prepared to assess instrument reprocessing practices, including high-level disinfection and sterilization to keep our patients and staffs safe. This paper presents 3 problems associated with instrument reprocessing practices in health care facilities, with a special emphasis on outpatient facilities: physical space problems, training and education problems, and lack of IPs’ presence. We offer solutions and mitigation strategies for these 3 problems. We also give some reflections on the current state of IP presence and responsibilities, and industry responsibilities, and we call for robust partnerships between IPs and the instrument reprocessing industry.