Type 2 Diabetes in Pregnancy - 23/07/19
, Harold David McIntyre, MD, FRACP b, c, Moshe Hod, MD b, dRésumé |
Hyperglycemia is common during pregnancy, involving multisystem adaptations. Pregnancy-induced metabolic changes increase insulin resistance. Pregnancy-induced insulin resistance adds to preexisting insulin resistance. Preexisting pancreatic β-cell defect compromises the ability to enhance insulin secretion, leading to hyperglycemia. Women with type 2 DM have similar rates of major congenital malformations, stillbirth, and neonatal mortality, but an even higher risk of perinatal mortality. In utero type 2 DM exposure confers greater risk and reduces time to development of type 2 DM in offspring. Preconception care to improve metabolic control in women with type 2 diabetes is critical.
Le texte complet de cet article est disponible en PDF.Keywords : Pregnancy hyperglycemia, Type 2 diabetes, Management
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| Disclosure: The authors have nothing to disclose. |
Vol 48 - N° 3
P. 511-531 - septembre 2019 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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