The relationship between inflammatory bowel disease and rosacea over the lifespan: A meta-analysis - 25/07/19
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
| pages | 6 |
| Iconographies | 2 |
| Vidéos | 0 |
| Autres | 0 |
Highlights |
• | A comprehensive search was performed for relevant English articles published up to 2018. |
• | Two sets of pooled risk estimates were calculated using fixed or random effects: the direction from IBD to rosacea and rosacea to IBD. |
• | Our meta-analysis confirmed a significant bi-directional association in occurrence of IBD and rosacea. |
Summary |
Backgrounds and aims |
It has been argued that the relationship between inflammatory bowel disease (IBD) and rosacea is bi-directional, but this hypothesis has not been explicitly tested. This systematic review examines the bi-directional prospective relationships between IBD and rosacea.
Methods |
A comprehensive search through PubMed and EMBASE was undertaken for studies investigating the association between two mainly forms of IBD [ulcerative colitis (UC) and Crohn's disease (CD)] and rosacea published in English until Jan 2018. Reviewers assessed the eligibility of each report by exposure/outcome measurement and study design. Two sets of pooled risk estimates were calculated using fixed or random effects: the direction from IBD to rosacea and rosacea to IBD.
Results |
Five publications on 13 separate study results involving 5,051,356 participants were eligible for this meta-analysis. A total of 6 outcomes established the direction of association from IBD to rosacea, and 7 outcomes examined the direction of association from rosacea to IBD. Compared to a non-rosacea population, the pooled RR (95% CI) for overall IBD, UC and CD were 1.32 (1.18–1.49), 1.19 (1.02–1.38) and 1.52 (1.25–1.84), respectively (P < 0.05). Meanwhile, the summary RR (95% CI) of rosacea in overall IBD, UC and CD patients were 1.66 (1.50–1.84), 1.69 (1.48–1.93) and 2.08 (1.26–3.46), respectively (P < 0.05).
Conclusion |
Our meta-analysis confirmed a significant bi-directional association in occurrence of IBD and rosacea. Future studies should specifically investigate possible shared pathophysiological mechanisms between the two disorders.
Le texte complet de cet article est disponible en PDF.Keywords : Inflammatory bowel disease, Rosacea, Meta-analysis
Plan
Vol 43 - N° 4
P. 497-502 - août 2019 Retour au numéro
Article précédent
- Online training on how to diagnose anoperineal lesions of Crohn's disease: Do pictures matter? A nationwide randomized study
- C. Geffrier, V. de Parades, L. Abramowitz, P. Benfredj, G. Bonnaud, C. Bord, D. Bouchard, G. Bouguen, F. Devulder, JM. Didelot, N. Fathallah, T. Higuero, X. Lesage, A. Nouts, P. Petit, F. Pigot, E. Pommaret, P. Roumeguere, L. Siproudhis, G. Staumont, JD. Zeitoun, P. Marteau
- Intraductal deployment of two fully covered metallic stents for anastomotic strictures following living donor liver transplantation
- Ben Warner, Deepak Joshi, Michael Heneghan, Parthi Srinivasan, Andreas Prachalias, Phillip Harrison
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?