Urodynamic Outcomes After Aquablation - 30/07/19


Abstract |
OBJECTIVES |
To compare urodynamic outcomes between Aquablation vs transurethral resection of the prostate (TURP).
METHODS |
Patients were randomized 2:1 (Aquablation:TURP) in the Waterjet Ablation Therapy for Endoscopic Resection of prostate tissue study. Urodynamics were measured at baseline and 6 months.
RESULTS |
Urodynamics studies were performed in 66 of the participating subjects at baseline and 6 month follow-up. At mean baseline pDet@qmax was 71 and 73cm H20 in the Aquablation and TURP groups, respectively (P = .7031). At 6-month follow-up, pDet@qmax decreased by 35 and 34cm H20, respectively (P < .0001 compared to baseline for both arms) with no significant difference in decrease across groups (P = .8919). A large negative shift in Bladder Outlet Obstruction Index was observed, consistent with a large reduction in the proportion of subjects with obstruction at follow-up compared to baseline (79% to 22% in Aquablation and 96% to 22% in TURP).
CONCLUSIONS |
In this trial, improvements after Aquablation in objective measures of bladder outlet obstruction were similar to those observed after TURP. ClinicalTrials.gov number, NCT02505919
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| Financial Disclosures: The study was funded by PROCEPT BioRobotics. No author has a conflict of interest with PROCEPT BioRobotics. |
Vol 126
P. 165-170 - avril 2019 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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