Over-EXTENDing the Window for Thrombolytic Therapy in Cerebrovascular Accident : September 2019 Annals of Emergency Medicine Journal Club - 23/08/19

Doi : 10.1016/j.annemergmed.2019.07.010

Rory J. Spiegel, MD ^a : Guest Contributor, John P. Donnelly, PhD ^b : Guest Contributor, Ryan P. Radecki, MD, MS ^c,^d : Guest Contributor
^a Department of Emergency Medicine, Washington Hospital Center, Washington, DC
^b Department of Learning Health Sciences, Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI
^c Department of Emergency Medicine, Northwest Permanente, Portland, OR
^d The University of Texas Health Science Center at Houston, Houston, TX

Section editors: Tyler W. Barrett, MD, MSCI; Ryan P. Radecki, MD, MS; Rory J. Spiegel, MD

Plan

Article in Review

What Question Did This Investigation Aim to Answer?

What Study Design Did the Authors Choose?

How Did the Authors Interpret the Results?

How Might This Study Affect Your Clinical Practice in the Emergency Department?

Discussion Points

	*Editor’s Note:*You are reading the 74th installment of Annals of Emergency Medicine Journal Club. As the Journal Club enters its second decade of publication, the format has been revised and will focus on a monthly succinct review of high-impact articles from this journal and other premier medical journals relevant to emergency medicine. The reviews are followed by questions demonstrating principles by which readers—be they clinicians, academics, residents, or medical students—may critically appraise the literature. We are interested in receiving feedback about this feature. Please e-mailjournalclub@acep.orgwith your comments.
	Authorship: All authors attest to meeting the four ICMJE.org authorship criteria: (1) Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND (2) Drafting the work or revising it critically for important intellectual content; AND (3) Final approval of the version to be published; AND (4) Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
	Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org). Dr. Donnelly was supported by the National Heart, Lung, and Blood Institute (no. K12-HL138039).