A cost-utility analysis comparing large volume displacement oncoplastic surgery to mastectomy with free flap reconstruction in the treatment of breast cancer - 05/09/19
, Ammar Asban b, Michael Jonczyk a, Lilian Chen a, Brian Czerniecki c, Carla S. Fisher dAbstract |
Purpose |
Breast cancer surgical treatment may include large volume displacement oncoplastic surgery (LVOS) or mastectomy with free flap reconstruction (MFFR). We investigated the cost-utility between LVOS versus MFFR to determine which approach was most cost-effective.
Methods |
A literature review was performed to calculate probabilities for clinical outcomes for each surgical option (LVOS versus MFFR), and to obtain utility scores that were converted into quality adjusted life years (QALYs) as measures for clinical effectiveness. Average Medicare payments were surrogates for cost. A decision tree was constructed and an incremental cost-utility ratio (ICUR) was used to calculate cost-effectiveness.
Results |
The decision tree demonstrates associated QALYs and costs with probabilities used to calculate the ICUR of $3699/QALY with gain of 2.7 QALY at an additional cost of $9987 proving that LVOS is a cost-effective surgical option. One-way sensitivity analysis showed that LVOS became cost-ineffective when its clinical effectiveness had a QALY of less than 30.187. Tornado Diagram Analysis and Monte-Carlo simulation supported our conclusion.
Conclusion |
LVOS is cost-effective when compared to MFFR for the appropriate breast cancer patient.
Clinical question/level of evidence |
II
Le texte complet de cet article est disponible en PDF.Highlights |
• | Options in treating breast cancer in patients with moderate or large sized breasts may include.
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• | This study investigates the cost-effectiveness of large volume displacement oncoplastic surgery when compared to mastectomy with free flap reconstruction. |
Plan
| ☆ | This paper was presented as a podium presentation at the 2017 Association of Plastic Surgeons Annual Meeting in Austin, TX. |
Vol 218 - N° 3
P. 597-604 - septembre 2019 Retour au numéro
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