General dentists usually serve as first-line providers for pediatric patients and the gateway to their oral health. Even though general dentists are trained to be able to treat children, dental education instruction can vary greatly. These differences heavily influence the individual practitioner’s knowledge base and comfort level in providing care to this vulnerable population. It is important for general dentists to be able to identify the presence of pediatric oral lesions. This article provides an overview of common pediatric oral lesions that general dentists may encounter in everyday practice.