Sex Differences in the Pathophysiology, Diagnosis, and Management of Aortic Stenosis - 19/11/19
Résumé |
For years, calcific aortic stenosis (AS) was considered to be similar in men and women, and the underrepresentation of women in research studies prevented any alternate conclusions. With new sex-specific studies and data, the landscape of AS is evolving and recently important sex-disparities were revealed. These sex-specific discrepancies are of utmost importance to stratify and personalize treatment according to sex. It is important and urgent to elucidate the sex-related differences and similarities in the pathophysiology of AS to develop and validate sex-specific approaches for the management and pharmacologic treatment of AS, and to improve clinical outcomes for both sexes.
Le texte complet de cet article est disponible en PDF.Keywords : Calcific aortic stenosis, Sex differences, Pathophysiology, Diagnosis, Outcome, Transcatheter aortic valve implantation, Surgical aortic valve replacement
Plan
| Conflict of Interest: Dr M-.A. Clavel has Core Lab contracts with Edwards Lifesciences, for which she receives no direct compensation; and research grant with Medtronic. The other author has no disclosure. |
Vol 38 - N° 1
P. 129-138 - février 2020 Retour au numéro
Article précédent
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