Bone Quality Measured Using Calcaneal Quantitative Ultrasonography Is Reduced Among Children with HIV in Johannesburg, South Africa - 21/11/19
Doi : 10.1016/j.jpeds.2019.07.018
Stephen M. Arpadi, MD, MS 1, 2, 3, ⁎ 
, Cara B. Thurman, RN, MPH 1, Faeezah Patel, MBBCh 4, Jonathan J. Kaufman, PhD 5, 6, Renate Strehlau, MBBCh 4, Megan Burke, MBBCh 4, Stephanie Shiau, PhD, MPH 1, 2, Ashraf Coovadia, MBBCh 4, Michael T. Yin, MD, MS 7
, Cara B. Thurman, RN, MPH 1, Faeezah Patel, MBBCh 4, Jonathan J. Kaufman, PhD 5, 6, Renate Strehlau, MBBCh 4, Megan Burke, MBBCh 4, Stephanie Shiau, PhD, MPH 1, 2, Ashraf Coovadia, MBBCh 4, Michael T. Yin, MD, MS 7 1 Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY
2 Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY
3 Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY
4 Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Department of Pediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
5 CyberLogic, Inc., New York, NY
6 Department of Orthopedics, The Mount Sinai Medical Center, New York, NY
7 Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY
∗Reprint requests: Stephen M. Arpadi, MD, MS, Columbia University, Mailman School of Public Health, Department of Epidemiology, GH Sergievsky Center, 622 W 168th St PH 19th Floor, New York, NY 10032.Columbia UniversityMailman School of Public HealthDepartment of EpidemiologyGH Sergievsky Center622 W 168th St PH 19th FloorNew YorkNY10032
Abstract |
We evaluated bone quality among South African children with HIV over a 2-year period by quantitative ultrasound (QUS). Children with HIV have persistently lower bone quality compared with controls reflecting increased porosity, reduced strength, and possibly an increased short- and long-term risk of fracture.
Le texte complet de cet article est disponible en PDF.Abbreviations : BAZ, BUA, DXA, QUS, SOS, SI, VL
Plan
| Funded by the National Institute of Child Health and Human Development (HD 073977 [to S.A. and M.Y.]). The authors declare no conflicts of interest. |
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| Portions of this study were presented at the International Workshop on HIV Pediatrics conference, July 20-21, 2018, Amsterdam, The Netherlands. |
© 2019
Elsevier Inc. Tous droits réservés.
Vol 215
P. 267 - décembre 2019 Retour au numéro
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