Research progress on classical traditional Chinese medicine formula Liuwei Dihuang pills in the treatment of type 2 diabetes - 30/11/19
pages | 7 |
Iconographies | 4 |
Vidéos | 0 |
Autres | 0 |
Graphical abstract |
Highlights |
• | Type 2 Diabetes symptoms similar to the manifestations of "Xiao Ke disease" in the TCM classics. |
• | Six Chinese medicinals for classical formula Liuwei Dihuang pills (LWP). |
• | LWP exerts therapeutic efficacy on the T2DM symptoms. |
• | Pharmacological mechanism and active compounds of LWP for treating T2DM. |
Abstract |
In traditional Chinese medicine (TCM), type 2 diabetes mellitus (T2DM) is regarded as Xiao Ke disease. Liuwei Dihuang pills (LWP), a classical TCM formula, with the function of nourishing kidney yin, has been used for treating Xiao Ke disease in clinic. In this review, we systematically highlighted recent evidence on LWP and T2DM data from clinical and animal studies, summarized the clinical application, pharmacological mechanism and the active compounds of LWP for the treatment of T2DM. This systematic review will provide an insightful understanding of TCM formulas, pharmacological mechanisms, medicinal-disease interactions, and will lay a foundation for the development of new drug therapy for T2DM.
Le texte complet de cet article est disponible en PDF.Abbreviation : LWP, T2DM, TCM, DM, RRP, RD, FC, CM, RA, PC, 5-HMF, TGF-β1, AEGs, PKC, RAS, DN, DPN, FPG, 2hPG, HbA1c, MAPK, NF-kB, EAR, IRS-1, IRS-2, IGF-1, BDNF, NO, OS, GA, PA, PG, PN, MR, LG, SR, PF, BPF, KEGG, HPLC
Keywords : Liuwei Dihuang pills, Type 2 diabetes, Xiao Ke disease, Pharmacological, Effective substance
Plan
Vol 121
Article 109564- janvier 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?