Rectal Swabs for Detecting Multidrug Resistant Bacteria Prior to Transrectal Prostate Fusion Biopsy: A Prospective Evaluation of Risk Factor Screening and Microbiologic Findings - 04/02/20
, Luis Busto Martin 1, Sami-Ramzi Leyh-Bannurah 2, Su Jung Oh-Hohenhorst 1, Mykyta Kachanov 1, Tobias Maurer 1, Sophie Knipper 1, Markus Graefen 1, Lars Budäus 1ABSTRACT |
Objective |
To assess the prevalence of fluoroquinolone resistant (QR) bacteria, multidrug resistant (MDR) bacteria and Enterococcus faecalis (E. faecalis) in rectal swabs of patients undergoing transrectal prostate biopsy and for evaluating if risk factor assessment is reliable for prediction of QR bacteria, MDR bacteria, or E. faecalis.
Patients and Methods |
Two hundred consecutive patients received a rectal swab examination prior to transrectal magnetic resonance imaging-guided fusion biopsy, for evaluating the prevalence of QR bacteria, MDR bacteria, and E. faecalis. The results of a standardized risk factor questionnaire, assessing known prognosticators for higher prevalence of resistant bacteria in rectal flora were correlated with the occurrence of QR bacteria, MDR bacteria, and E. faecalis in rectal swabs.
Results |
QR E. coli was detected in 12 patients (6%). Regarding MDR bacteria, extended spectrum β- lactamase- producing E. coli occurred in 8 patients (4%). E. faecalis was found in 15 patients (7.5%). A total of 193 patients completed the risk factor questionnaire. Of those, 107 (53.2%) patients harbored no risk factors, while 86 (42.8%) had at least 1 risk factor, of which the most common was repeat biopsy. No association was found between any risk factor and occurrence of QR bacteria, MDR bacteria, or E. faecalis (P >.05).
Conclusion |
The prevalence of resistant germs in our cohort was lower compared to other series. Moreover, the rate of QR bacteria, MDR bacteria, or E. faecalis in rectal swabs was not reliably associated with risk factor assessment.
Le texte complet de cet article est disponible en PDF.Plan
| Authors’ Contributions: C Würnschimmel: Project development, data collection, manuscript writing/editing; L Busto: Data collection; SR Leyh-Bannurah: Supervision, manuscript editing; SJ Oh-Hohenhorst: Manuscript editing; M Kachanov: Manuscript editing; T Maurer: Manuscript editing; S Knipper: Data analysis, manuscript editing; M Graefen: Supervision, manuscript editing; L Budäus: Project development, supervision, manuscript editing. |
|
| Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. |
|
| Compliance with ethical standards/Research involving Human Participants: This study was performed in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments. |
|
| Informed consent: Informed consent was obtained from all individual participants included in the study. |
Vol 136
P. 127-132 - février 2020 Retour au numéro
Article précédent
- AUTHOR REPLY
- David Baunoch
- A Systematic Review and Evidence-based Analysis of Ingredients in Popular Male Fertility Supplements
- Manish Kuchakulla, Yash Soni, Premal Patel, Neel Parekh, Ranjith Ramasamy
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?