Endothelial Glycocalyx - 13/03/20
Résumé |
The endothelial glycocalyx (EG) is the most luminal layer of the blood vessel, growing on and within the vascular wall. Shedding of the EG plays a central role in many critical illnesses. Degradation of the EG is associated with increased morbidity and mortality. Certain illnesses and iatrogenic interventions can cause degradation of the EG. It is not known whether restitution of the EG promotes the survival of the patient. First trials that focus on the reorganization and/or restitution of the EG seem promising. Nevertheless, the step “from bench to bedside” is still a big one.
Le texte complet de cet article est disponible en PDF.Keywords : Endothelial glycocalyx, Shedding, Septic injury, Organ dysfunction, ARDS, AKI, Trauma
Plan
| The authors declare to have no conflict of interest in writing this article. |
Vol 36 - N° 2
P. 217-232 - avril 2020 Retour au numéro
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