Drugs Used in Circadian Sleep-Wake Rhythm Disturbances - 08/05/20
, Jonathan S. Emens, MD b, cRésumé |
This article focuses on melatonin and other melatonin receptor agonists, and specifically their circadian phase shifting and sleep-enhancing properties. The circadian system and circadian rhythm sleep-wake disorders are briefly reviewed, followed by a summary of the circadian phase shifting, sleep-enhancing properties, and possible safety concerns associated with melatonin and other melatonin receptor agonists. The recommended use of melatonin, including dose and timing, in the latest American Academy of Sleep Medicine Clinical Practice Guidelines for the treatment of intrinsic circadian rhythm disorders is also reviewed. Lastly, the practical aspects of treatment and consideration of clinical treatment outcomes are discussed.
Le texte complet de cet article est disponible en PDF.Keywords : Advance, Agonist, Circadian, Delay, Melatonin, Shift, Sleep
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| This article originally appeared in June, 2018 issue of Sleep Medicine Clinics (Volume 13, Issue 2). |
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| Disclosure: H.J. Burgess is a consultant for Natrol, LLC. J.S. Emens has nothing to disclose. |
Vol 15 - N° 2
P. 301-310 - juin 2020 Retour au numéro
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