Should we consider paranasal and chest computed tomography in severe asthma patients? - 03/08/20
, D. Romero a, J. Fernández-Lahera a, C. Villasante a, I. Pinilla b, P. Barranco c, J. Dominguez-Ortega c, R. Álvarez-Sala Walther R a, dAbstract |
Background |
It is essential to recognize and treat findings that can simulate or worsen symptoms to improve asthma control and thereby to reduce costs. Guidelines highlight a paranasal (PS) and chest computed tomography (CT) scan as a tool for disease evaluation and, although they suggest its indication in patients whom presentation is atypical, there are not well-defined criteria.
Objectives |
To describe the most common findings in the PS and chest CT in severe asthma patients and to analyse the characteristics of asthmatics with the finding of nasal polyps or bronchiectasis.
Methods |
We retrospectively reviewed the medical records of 161 adults with confirmed severe asthma who had undergone to PS and/or chest CT. Clinical data from their electronic health record and the findings from a PS and/or chest CT within the last five years were collected.
Results |
In the PS CT, 70.5% of patients presented mucous thickening and 46.7% presented nasal polyps. Both findings were associated with male gender and level of blood eosinophils. In chest CT, 28% of individuals showed atelectasis, 16.5% air trapping, 17.7% affectation of the small airway, 11.6% pulmonary infiltrates and 10.4% emphysema. Bronchiectasis were identified in 60.4% of subjects, who were older and had poorer lung function.
Conclusion |
Paranasal and thoracic computed tomography are important tools in the treatment of severe asthma because they allow us to detect highly prevalent findings in this disease that can lead to poorer control of it.
Le texte complet de cet article est disponible en PDF.Highlights |
• | 70.5% of severe asthma patients exhibited mucous thickening and almost 47% presented nasal polyps. |
• | Bronchiectasis were identified in more than 60% of severe asthma subjects who accomplished a chest computed tomography. |
• | We should consider paranasal and chest computed tomography in every severe asthma patient to identify findings that can worsen asthma control. |
Keywords : Severe asthma, Computed tomography, Control
Plan
Vol 169
Article 106013- août 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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