Six-year multicenter study on short-term peripheral venous catheters-related bloodstream infection rates in 204 intensive care units of 57 hospitals in 19 cities of India: International Nosocomial Infection Control Consortium (INICC) findings - 26/08/20
, Debkishore Gupta, MD b, Prasad Rajhans, MD c, Sheila Nainan Myatra, MD d, S. Muralidharan, MD e, Yatin Mehta, MD f, Mohit Kharbanda, MD g, Camilla Rodrigues, MD h, Arpita Dwivedy, MD i, Sweta Shah, MD j, Aruna Poojary, MD k, Subhash Kumar Todi, MD l, Supriya Chabukswar, MD m, Mahuya Bhattacharyya, MD n, Bala Ramachandran, MD o, Nagarajan Ramakrishnan, MD p, Sujit Kar Purkayasta, MD q, Asmita Sagar Sakle, MD r, Siva Kumar, MD s, Anup R. Warrier, MD t, Maithili Satish Kavathekar, MD u, Samir Sahu, MD v, Aisha Mubarak, MD w, Nikhil Modi, MD x, Namita Jaggi, MD y, Nadimpalli Gita, MD z, Shakti Bedanta Mishra, MD aa, Suneeta Sahu, MD bb, Burhan Jawadwala, MD cc, Dolatsinh Zala, MD dd, Tenzin Zompa, MD ee, Purva Mathur, MD ff, Suhas Nirkhiwale, MD gg, Sonali Vadi, MD hh, Sanjeev Singh, MD ii, Manoj Agarwal, MD jj, Nagamani Sen, MD kk, Anil Karlekar, MD ll, D.P. Punia, MD mm, Suresh Kumar, MD nn, Ramachadran Gopinath, MD oo, Pravin Kumar Nair, MD pp, Murali Chakravarthy, MD qq, Kavita Sandhu, MD rr, Chandrika Kambam, MD ss, Salil Kumar Mohanty, MD tt, Ami Varaiya, MD uu, Nirav Pandya, MD vv, Vaibhavi R. Subhedar, MD ww, M.R. Vanajakshi, MD xx, Deepak Singla, MD yy, Mayur Patel, MD zzHighlights |
• | We report peripheral venous catheters (PVC)-related BSI rates from 2013 to 2019. |
• | We collected prospective data from 204 ICUs in 57 hospitals in 19 cities of India. |
• | We followed 7,513 ICU patients for 296,893 bed-days and 295,795 PVC-days. |
• | We identified 863 PVC-related BSIs, amounting to a rate of 2.91/1,000 PVC-days. |
Résumé |
Background |
Short-term peripheral venous catheters-related bloodstream infections (PVCR-BSIs) rates have not been systematically studied in developing countries, and data on their incidence by number of device-days are not available.
Methods |
Prospective, surveillance study on PVCR-BSI conducted from September 1, 2013 to May 31, 2019 in 204 intensive care units (ICUs), members of the International Nosocomial Infection Control Consortium (INICC), from 57 hospitals in 19 cities of India. We applied US INICC definition criteria and reported methods using the INICC Surveillance Online System.
Results |
We followed 7,513 ICU patients for 296,893 bed-days and 295,795 short term peripheral venous catheter (PVC)-days. We identified 863 PVCR-BSIs, amounting to a rate of 2.91/1,000 PVC-days.
Mortality in patients with PVC but without PVCR-BSI was 4.14%, and 11.59% in patients with PVCR-BSI. The length of stay in patients with PVC but without PVCR-BSI was 4.13 days, and 5.9 days in patients with PVCR-BSI. The micro-organism profile showed 68% of gram negative bacteria: Escherichia coli (23%), Klebsiella spp (15%), Pseudomonas aeruginosa (5%), and others. The predominant gram-positive bacteria were Staphylococcus aureus (10%).
Conclusions |
PVCR-BSI rates found in our ICUs were much higher than rates published from industrialized countries. Infection prevention programs must be implemented to reduce the incidence of PVCR-BSIs.
Le texte complet de cet article est disponible en PDF.Key Words : Hospital infection, Device-associated infections, Antibiotic resistance, Peripheral line-associated bloodstream infections, Mortality, Surveillance
Plan
| For a list of all the members of the International Nosocomial Infection Control Consortium (INICC) and all the co-authors of this study, see the Appendix with remaining authors. |
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| Conflicts of interest: All authors report no conflicts of interest related to this article. Institutional Review Boards agreed to the study protocol, and patient confidentiality was protected by codifying the recorded information, making it only identifiable to the infection control team. |
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| Funding: The funding for the activities carried out at INICC head quarters were provided by the corresponding author, Victor D. Rosenthal, and the Foundation to Fight against Nosocomial Infections. |
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| Author contributions: All authors were involved in drafting of the manuscript, provision of study patients, collection of data, critical revision of the manuscript for important intellectual content, and final approval of the manuscript. V.D.R. was responsible for study conception and design; software development; data assembly, analysis, and interpretation; epidemiologic analysis; statistical analysis; administrative, technical, and logistical support. |
Vol 48 - N° 9
P. 1001-1008 - septembre 2020 Retour au numéro
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