Susceptibility of SARS-CoV-2 to UV irradiation - 22/09/20

Highlights |
• | SARS-CoV-2 is highly susceptible to irradiation with ultraviolet light. |
• | High viral loads of 5 * 106 TCID50/ml SARS-CoV-2 can be inactivated in 9 minutes by UVC irradiation. |
• | UVC irradiation represents a suitable disinfection method for SARS-CoV-2. |
Abstract |
The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 106 TCID50/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm2. UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.
Le texte complet de cet article est disponible en PDF.Key Words : COVID-19, Ultraviolet light, Inactivation
Plan
| Conflicts of interest: None to report. |
|
| Author Contributions: C.S. Heilingloh, U. Dittmer, O. Witzke: study design, data collection, data interpretation; U.W. Aufderhorst, L. Schipper, M. Alt: experiments, data analysis, data interpretation; D. Yang, X. Zheng, K. Sutter, M. Trilling: data analysis, data interpretation; writing; C.S. Heilingloh, E. Steinmann, A. Krawczyk study design, writing, figure design. |
Vol 48 - N° 10
P. 1273-1275 - octobre 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
