Silicosis: An Update and Guide for Clinicians - 04/11/20

Doi : 10.1016/j.ccm.2020.08.012

Silpa Krefft, MD, MPH ^a,^b,^c,^d,^⁎ , Jenna Wolff, BA ^a, Cecile Rose, MD, MPH ^a,^c,^d
^a Division of Environmental and Occupational Health Sciences, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA
^b Division of Pulmonary and Critical Care Medicine, VA Eastern Colorado Health Care System, Aurora, CO, USA
^c Division of Pulmonary and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
^d Department of Environmental and Occupational Health, Colorado School of Public Health, Aurora, CO, USA

^∗Corresponding author. Division of Environmental and Occupational Health Sciences, National Jewish Health, 1400 Jackson Street, Denver, CO 80206.Division of Environmental and Occupational Health SciencesNational Jewish Health1400 Jackson StreetDenverCO80206

Résumé

This overview provides an update on silicosis epidemiology with review of exposures and emerging trends in acute and accelerated silicosis in the twenty-first century. The silicosis epidemics in mining, denim sandblasting, and engineering stone industries are highlighted. Clinical presentations of silicosis and silica-related conditions such as autoimmune, kidney, and mycobacterial disease, as well as lung cancer, are discussed. Important aspects of the new OSHA 2017 Silica Standard are presented. This review also includes practical guidance for clinicians to address questions that may arise when evaluating silica-exposed patients and to the public health responses needed following a diagnosis of silica-related disease.

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Keywords : Silicosis, Silicoproteinosis, Acute silicosis, Accelerated silicosis, OSHA Silica standard