Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ?65 Years of Age With a Low Ejection Fraction After Coronary Revascularization - 10/12/20
, Shuang Li, MS b, Di Lu, MS b, Roland A. Matsouaka, PhD b, Jennifer Rymer, MD, MBA a, b, Gregg C. Fonarow, MD c, James A. de Lemos, MD d, Eric Peterson, MD, MPH a, b, Sean D. Pokorney, MD, MBA a, b, Tracy Wang, MD, MHS, MSc a, b, Sana M. Al-Khatib, MD, MHS a, bRésumé |
The purpose of this analysis was to assess implantable cardioverter-defibrillator (ICD) utilization and its association with mortality among patients ≥65 years of age after coronary revascularization. Patients in the National Cardiovascular Database Registry Chest Pain-Myocardial Infarction (MI) Registry who presented with MI from January 2, 2009 to December 31, 2016, had a left ventricular ejection fraction ≤35% and underwent in-hospital revascularization (10,014 percutaneous coronary intervention (PCI) and 1,647 coronary artery bypass grafting (CABG)) were linked with Medicare claims to determine rates of 1-year ICD implantation. The association between ICD implantation and 2-year mortality was assessed. Of 11,661 included patients, an ICD was implanted in 1,234 (10.6%) within 1 year of revascularization (1,063 (10.6%) PCI and 171 (10.4%) CABG). Among PCI-treated patients, in-hospital ventricular arrhythmia (adjusted hazard ratio [aHR] 1.60, 95% confidence interval [CI] 1.34 to 1.92), 2-week cardiology follow-up (aHR 1.48, 95% CI 1.29 to 1.70), readmission for heart failure (aHR 3.21, 95% CI 2.73 to 3.79), and readmission for MI (aHR 2.18, 95% CI 1.66 to 2.85) were positively associated with ICD implantation. Among CABG-treated patients, in-hospital ventricular arrhythmia (aHR 2.33, 95% CI 1.39 to 3.91), and heart failure readmission (aHR 3.14, 95% CI 1.96 to 5.04) were positively associated with ICD implantation. Women were less likely to receive an ICD, regardless of the revascularization strategy. ICD implantation was associated with lower 2-year all-cause mortality (aHR 0.74, 95% CI 0.63 to 0.86). In conclusion, only 1 in 10 Medicare patients with low ejection fraction received an ICD within 1 year after revascularization. Contact with the healthcare system after discharge was associated with higher likelihood of ICD implantation. ICD implantation was associated with lower mortality following revascularization for MI.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Only 10% of Medicare patients with low LVEF after coronary revascularization for MI received an ICD within 1 year of hospital discharge, regardless of revascularization strategy. |
• | Patient contact with the healthcare system after discharge, either through early cardiology follow-up or readmission, was associated with a higher likelihood of ICD implantation within 1 year. |
• | Women were less likely to receive an ICD compared with men. |
• | Among eligible older patients, ICD implantation within 1 year of revascularization was associated with lower adjusted 2-year mortality. |
Plan
| Sources of Funding: This research was supported by the American College of Cardiology's National Cardiovascular Data Registry (NCDR). The views expressed in this manuscript represent those of the authors and do not necessarily represent the official views of the NCDR or its associated professional societies. |
Vol 138
P. 26-32 - janvier 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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