Screening for perinatal depression with the Patient Health Questionnaire depression scale (PHQ-9): A systematic review and meta-analysis - 23/01/21
, Kurt Kroenke a, b, ⁎ , Timothy E. Stump c, Patrick O. Monahan cAbstract |
Objectives |
Perinatal depression (PND) is a prevalent and disabling problem both during pregnancy and the postpartum period. The legacy screening measure has been the Edinburgh Postnatal Depression Scale (EPDS). This systematic review examines the validity of the PHQ-9 as a screener for PND.
Methods |
The following databases were searched from January 2001 (when the PHQ-9 was first published) through June 2020: MEDLINE, Embase, and PsychInfo. Studies that compared the PHQ-9 to a criterion standard psychiatric interview were used to determine the operating characteristics of sensitivity, specificity and area under the curve (AUC). Studies comparing the PHQ-9 to the EPDS and other depression scales evaluated convergent validity.
Results |
A total of 35 articles were eligible for criterion (n = 10) or convergent (n = 25) validity. Meta-analysis of the 7 criterion validity studies using the standard PHQ-9 cut point ≥10 showed a pooled sensitivity, specificity and AUC of 0.84, 0.81 and 0.89, respectively. Operating characteristics of the PHQ-9 and EPDS were nearly identical in head-to-head comparison studies. The median correlation between the PHQ-9 and EPDS was 0.59, and categorical agreement was moderate.
Conclusions |
The PHQ-9 appears to be a viable option for perinatal depression screening with operating characteristics similar to the legacy EPDS.
Le texte complet de cet article est disponible en PDF.Highlights |
• | The PHQ-9 has good sensitivity and specificity in screening for perinatal depression |
• | Operating characteristics of the PHQ-9 are similar to the Edinburgh Postnatal Depression Scale |
• | Both scales are viable options for use in women during pregnancy and the postpartum period. |
Keywords : Depression, Screening, Pregnancy, Postpartum, Perinatal, PHQ-9
Plan
Vol 68
P. 74-82 - janvier 2021 Retour au numéro
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