Statewide Price Variation for Generic Benign Prostatic Hyperplasia Medications - 03/02/21
, Praveen Kumar 2 , Ayodele G. Ogunmola 3 , Omar Ayyash 1 , Jonathan G. Yabes 2 , Lindsay M. Sabik 2 , Anobel Y. Odisho 4 , Jathin Bandari 1 , Liam C. Macleod 1 , Benjamin J. Davies 1 , Bruce L. Jacobs 1 ABSTRACT |
Objective |
To examine the geographic and pharmacy-type variation in costs for generic benign prostatic hyperplasia (BPH) medications in order to improve drug price transparency and reduce health disparities. Medical therapy for BPH can be expensive, having significant implications for uninsured and underinsured patients.
Methods |
We generated a 20% random sample of all pharmacies in Pennsylvania and queried each for the uninsured cash price of a 30-day prescription of tamsulosin 0.4mg daily, finasteride 5mg daily, oxybutynin immediate release 5mg TID and oxybutynin XL 10mg daily. Our primary objectives were to identify price variation based on pharmacy type (i.e., big chain and independent) and between geographic regions (predetermined by the Pennsylvania Health Care Cost Containment Council Database). We fit multivariable quantile regression models to test for an association between drug price and region after controlling for pharmacy type.
Results |
Among 575 retail pharmacies contacted, 473 responded (82% response rate). The median cash price was significantly higher for big chain pharmacies than for independent pharmacies for tamsulosin ($66 vs. $15), finasteride ($68 vs. $15), oxybutynin immediate release ($49 vs. $35), and oxybutynin XL ($79 vs. $31) (all p < 0.05). When controlling for region, the median and 75th percentile price of all drugs was significantly higher for big chain pharmacies. When controlling for pharmacy type, regional variation was noted in all four drugs at the 75th percentile price and was greater for independent pharmacies.
Conclusion |
Compared to independent pharmacies, big chain pharmacies charged significantly more for generic BPH medications to uninsured patients. However, independent pharmacies demonstrated more regional variation in their pricing.
Le texte complet de cet article est disponible en PDF.Plan
| Funding/Disclosures: Bruce Jacobs is supported in part by P30CA047904 from the National Cancer Institute, the Henry L. Hillman Foundation, the Shadyside Hospital Foundation, and the University of Pittsburgh O'Brien Cooperative Research Center Program (U54-DK112079). Lindsay Sabik is supported in part by National Cancer Institute Cancer Center Support Grant P30 CA047904. |
|
| Author Contributions: Anup Shah: conception and design, data analysis and interpretation, statistical analysis, drafting and revision of manuscript, critical revision of manuscript, final approval of manuscript. |
|
| Praveen Kumar: conception and design, data analysis and interpretation, statistical analysis, critical revision of manuscript, final approval of manuscript. |
|
| Ayodele G. Ogunmola: conception and design, data analysis and interpretation, critical revision of manuscript, final approval of manuscript. |
|
| Omar Ayyash: conception and design, data analysis and interpretation, statistical analysis, critical revision of manuscript, final approval of manuscript. |
|
| Jonathan Yabes: conception and design, data analysis and interpretation, statistical analysis, critical revision of manuscript, final approval of manuscript. |
|
| Lindsay Sabik: conception and design, data analysis and interpretation, statistical analysis, critical revision of manuscript, final approval of manuscript. |
|
| Anobel Odisho: data analysis and interpretation, statistical analysis, critical revision of manuscript, final approval of manuscript. |
|
| Jathin Bandari: data analysis and interpretation, critical revision of manuscript, final approval of manuscript. |
|
| Liam Macleod: conception and design, data analysis and interpretation, critical revision of manuscript, final approval of manuscript. |
|
| Benjamin Davies: conception and design, data analysis and interpretation, critical revision of manuscript, final approval of manuscript. |
|
| Bruce Jacobs: conception and design, data analysis and interpretation, statistical analysis, drafting and revision of manuscript, critical revision of manuscript, final approval of manuscript. |
Vol 148
P. 224-229 - février 2021 Retour au numéro
Article précédent
- Suboptimal Prediction of Clinically Significant Prostate Cancer in Radical Prostatectomy Specimens by mpMRI-Targeted Biopsy
- Nejdet Karsiyakali, Mahir Bulent Ozgen, Bora Ozveren, Cem Akbal, Alp Dincer, Haydar Durak, Levent Turkeri
- Association Between Lower Urinary Tract Symptoms and Frailty in Older Men Presenting for Urologic Care
- Scott R. Bauer, Chengshi Jin, Puneet Kamal, Anne M. Suskind
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?