Epileptogenic Network Formation - 23/02/21
, Alessandro De Benedictis, MD, PhD b, 1, Nicola Specchio, MD, PhD a, Carlo Efisio Marras, MD bRésumé |
Epilepsy is characterized by specific alterations in network organization. The main parameters at the basis of epileptogenic network formation are alterations of cortical thickness, development of pathologic hubs, modification of hub distribution, and white matter alterations. The effect is a reinforcement of brain connectivity in both the epileptogenic zone and the propagation zone. Moreover, the epileptogenic network is characterized by some specific neurophysiologic biomarkers that evidence the tendency of the network itself to shift from an interictal state to an ictal one. The recognition of these features is crucial in planning epilepsy surgery.
Le texte complet de cet article est disponible en PDF.Keywords : Epilepsy surgery, Epileptogenic network, Epileptogenesis, Propagation network
Plan
Vol 31 - N° 3
P. 335-344 - juillet 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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