Berlin Heart EXCOR Paediatric Ventricular Assist Device: Does Weight Matter? - 16/03/21
, Célia Gran, MD a, b, Roland Henaine, MD, PhD d, François Roubertie, MD, PhD e, Caroline Chenu, MD a, Marion Fiorini, MD f, Stéphane Le Bel, MD f, Philippe Mauriat, MD, PhD g, Jean Neidecker, MD h, Loïc Macé, MD, PhD a, b, Bernard Kreitmann, MD, PhD e, Caroline Ovaert, MD, PhD b, cAbstract |
Background |
Berlin Heart EXCOR (BH) ventricular assist devices provide mechanical long-term circulatory support in children with end-stage heart failure, as a bridge to transplantation or to recovery. Most studies are from large-volume paediatric cardiac centres.
Aim |
The aim of this study was to analyse the experiences of three French centres and to compare these with available published data.
Method |
We performed a retrospective observational study of three paediatric cardiac intensive care units. All children supported with BH devices were included. Morbidity and mortality data were collected and risk factors analysed.
Results |
Fifty-four (54) patients (54% male) were included. Survival rate was 73% while on a BH device. Median age at BH device implantation was 17 months (range 2–180 months). The predominant indication was dilated cardiomyopathy (61%). Bi-ventricular assist device was used in 25 (46%) cases. The total length of long-term circulatory support was 3,373 days, with a mean length per patient of 62.5 days (range 5–267 days). Thirty-two (32) patients were transplanted (59%) and seven (13%) were successfully weaned. Type and length of support did not influence morbidity. Main complications were renal dysfunction (57%), bleeding (41%), and infection (39%). In multivariate analysis, a weight <5 kg was significantly associated with higher mortality.
Conclusions |
The weight seems to be the most important risk factor of mortality in this precarious condition.
Le texte complet de cet article est disponible en PDF.Keywords : Ventricular failure, Assist device, Cardiomyopathy, Children
Plan
Vol 30 - N° 4
P. 585-591 - avril 2021 Retour au numéro
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