Standardized Feeding Approach Mitigates Weight Loss in Infants with Congenital Heart Disease - 22/03/21
Abstract |
Objective |
To evaluate the effect of a standardized feeding approach using a clinical nutrition pathway on weight-for-age Z score (WAZ) over hospital length of stay (HLOS) for infants with congenital heart disease (CHD).
Study design |
A 10-year retrospective cohort study examined eligible infants who underwent neonatal cardiac surgery between July 2009 and December 2018 (n = 987). Eligibility criteria included infants born at least 37 weeks of gestation and a minimum birth weight of 2 kg who underwent cardiac surgery for CHD within the first 30 days of life. Using the best linear unbiased predictions from a linear mixed effects model, WAZ change over HLOS was estimated before and after January 2013, when the standardized feeding approach was initiated. The best linear unbiased predictions model included adjustment for patient characteristics including sex, race, HLOS, and class of cardiac defect.
Results |
The change in WAZ over HLOS was significantly higher from 2013 to 2018 than from 2009 to 2012 (β = 0.16; SE = 0.02; P < .001), after controlling for sex, race, HLOS, and CHD category, indicating that infants experienced a decreased WAZ loss over HLOS after the standardized feeding approach was initiated. Additionally, differences were found in WAZ loss over HLOS between infants with single ventricle CHD (β = 0.26; SE = 0.04; P < .001) and 2 ventricle CHD (β = 0.04; SE = 0.02; P = .04).
Conclusions |
These data suggest that an organized, focused approach for nutrition therapy using a standardized pathway improves weight change outcomes before hospital discharge for infants with single and 2 ventricle CHD who require neonatal cardiac surgery.
Le texte complet de cet article est disponible en PDF.Keywords : growth, nutrition, feeding, critical care, congenital heart disease
Abbreviations : CHD, CICU, HLOS, NEC, PC4, WAZ
Plan
| Portions of this study were presented at the American Heart Association scientific meeting, November 16-18, 2019. |
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| This project was Supported by the Cardiac Center Research Core at Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States. A.L. was also supported by the National Institutes for Nursing Research, United States, T32NR007100. The authors declare no conflicts of interest. |
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| this should be after funding information |
Vol 231
P. 124 - avril 2021 Retour au numéro
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