Médecine

Paramédical

Autres domaines


S'abonner

Pneumonia severity indices predict prognosis in coronavirus disease-2019 - 11/06/21

Doi : 10.1016/j.resmer.2021.100826 
E.S. Ucan a, A. Ozgen Alpaydin a, , S.S. Ozuygur a, S. Ercan a, B. Unal b, A.A. Sayiner c, B. Ergan a, N. Gokmen d, Y. Savran e, O. Kilinc a, V. Avkan Oguz f

DEU COVID Study Group1

  DEU COVID Study Group (in alphabetical order): Firat Bayraktar, M.D., Caner Cavdar, M.D., Sema Alp Cavus, M.D., Ziya Kuruuzum, M.D., Can Sevinc, M.D., Gokcen Omeroglu Simsek, M.D., Isıl Somali, M.D, Mujde Soyturk, M.D., Kemal Can Tertemiz, M.D., Serkan Yildiz, M.D.

a Department of Pulmonary Diseases, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey 
b Department of Public Health, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey 
c Department of Medical Microbiology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey 
d Department of Anesthesiology and Reanimation, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey 
e Department of Internal Medicine, Medicana International Izmir Hospital, Izmir, Turkey 
f Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey 

Corresponding Author: Department of Pulmonary Diseases, Dokuz Eylul University Faculty of Medicine, Inciraltı 35340 Izmir, Turkey.Department of Pulmonary Diseases, Dokuz Eylul University Faculty of MedicineInciraltı Izmir35340Turkey

Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.

Connectez-vous pour en bénéficier!

Abstract

Background

Early recognition of the severe illness is critical in coronavirus disease-19 (COVID-19) to provide best care and optimize the use of limited resources.

Objectives

We aimed to determine the predictive properties of common community-acquired pneumonia (CAP) severity scores and COVID-19 specific indices.

Methods

In this retrospective cohort, COVID-19 patients hospitalized in a teaching hospital between 18 March-20 May 2020 were included. Demographic, clinical, and laboratory characteristics related to severity and mortality were measured and CURB-65, PSI, A-DROP, CALL, and COVID-GRAM scores were calculated as defined previously in the literature. Progression to severe disease and in-hospital/overall mortality during the follow-up of the patients were determined from electronic records. Kaplan-Meier, log-rank test, and Cox proportional hazard regression model was used. The discrimination capability of pneumonia severity indices was evaluated by receiver-operating-characteristic (ROC) analysis.

Results

Two hundred ninety-eight patients were included in the study. Sixty-two patients (20.8%) presented with severe COVID-19 while thirty-one (10.4%) developed severe COVID-19 at any time from the admission. In-hospital mortality was 39 (13.1%) while the overall mortality was 44 (14.8%). The mortality in low-risk groups that were identified to manage outside the hospital was 0 in CALL Class A, 1.67% in PSI low risk, and 2.68% in CURB-65 low-risk. However, the AUCs for the mortality prediction in COVID-19 were 0.875, 0.873, 0.859, 0.855, and 0.828 for A-DROP, PSI, CURB-65, COVID-GRAM, and CALL scores respectively. The AUCs for the prediction of progression to severe disease was 0.739, 0.711, 0,697, 0.673, and 0.668 for CURB-65, CALL, PSI, COVID-GRAM, A-DROP respectively. The hazard ratios (HR) for the tested pneumonia severity indices demonstrated that A-DROP and CURB-65 scores had the strongest association with mortality, and PSI, and COVID-GRAM scores predicted mortality independent from age and comorbidity.

Conclusion

Community-acquired pneumonia (CAP) scores can predict in COVID-19. The indices proposed specifically to COVID-19 work less than nonspecific scoring systems surprisingly. The CALL score may be used to decide outpatient management in COVID-19.

Le texte complet de cet article est disponible en PDF.

Keywords : CAP, COVID-19, CALL score, COVID-GRAM score, Pneumonia severity indices, A-DROP, CURB-65, PSI, PSI/PORT


Plan


© 2021  SPLF and Elsevier Masson SAS. Tous droits réservés.
Ajouter à ma bibliothèque Retirer de ma bibliothèque Imprimer
Export

    Export citations

  • Fichier

  • Contenu

Vol 79

Article 100826- mai 2021 Retour au numéro
Article précédent Article précédent
  • Spirometric restrictive ventilatory pattern and type 2 diabetes mellitus in a tertiary hospital in Cameroon: A comparative study
  • S.E. Ndouga, V. Poka-Mayap, A. Dodo Balkissou, A. Djenabou, A. Kuaban, A. Haman, A. Ofimboudem-Nguetsa, E. Sobngwi, E.W. Pefura-Yone
| Article suivant Article suivant
  • Sampling strategy for bacteriological diagnosis of intrathoracic tuberculosis
  • T. Maitre, V. Ok, F. Morel, I. Bonnet, W. Sougakoff, J. Robert, V. Trosini, E. Caumes, A. Aubry, N. Veziris

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

Mon compte


Plateformes Elsevier Masson

Déclaration CNIL

EM-CONSULTE.COM est déclaré à la CNIL, déclaration n° 1286925.

En application de la loi nº78-17 du 6 janvier 1978 relative à l'informatique, aux fichiers et aux libertés, vous disposez des droits d'opposition (art.26 de la loi), d'accès (art.34 à 38 de la loi), et de rectification (art.36 de la loi) des données vous concernant. Ainsi, vous pouvez exiger que soient rectifiées, complétées, clarifiées, mises à jour ou effacées les informations vous concernant qui sont inexactes, incomplètes, équivoques, périmées ou dont la collecte ou l'utilisation ou la conservation est interdite.
Les informations personnelles concernant les visiteurs de notre site, y compris leur identité, sont confidentielles.
Le responsable du site s'engage sur l'honneur à respecter les conditions légales de confidentialité applicables en France et à ne pas divulguer ces informations à des tiers.