Association of insomnia with mania in Lebanese patients with bipolar disorder - 21/07/21
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Abstract |
Objective |
To assess: (1) the association between insomnia experienced at admission, sociodemographic and other patients’ characteristics and mania; and (2) the variation of insomnia and mania before and after treatment in bipolar patients with manic episodes (type I).
Methods |
Sixty-two patients were interviewed shortly after their admission to the hospital (after 3 to 5 days). The current symptoms experienced by the patients were assessed upon admission and again at discharge from the hospital.
Results |
A poorer quality of sleep (higher PSQI scores) (Beta=0.590) was significantly associated with higher mania, whereas the intake of SSRIs (Beta=−5.952) and TCAs (Beta=−8.181) was significantly associated with lower mania. Furthermore, highly significant reductions were reported in the PSQI scores (4.96 vs. 2.75, P<0.001), ISI scores (8.30 vs. 3.45, P<0.001) and YMRS scores (8.60 vs. 3.06, P<0.001) between admission to and discharge from the hospital.
Conclusion |
Insomnia in patients with bipolar disorder type I is associated with mania, with a significant reduction of sleep problems seen during a period of approximately 20 days of hospitalization. Further longitudinal studies are needed to confirm the validity of our results and identify the causes. In the meantime, this research recommends a strategy to improve sleeplessness experienced during inter-episode phases may be helpful in preventing manic episodes in BD.
Le texte complet de cet article est disponible en PDF.Keywords : Bipolar disorder, Insomnia, Sleep, Mania
Plan
☆ | This work has been done in the frame of the “Behavioral and Cognitive Neuroscience Master 2 program”, Faculty of Sciences, Lebanese University. |
Vol 47 - N° 4
P. 314-318 - août 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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