Propensity score–matched comparison between totally laparoscopic right hemicolectomy with transcolonic natural orifice specimen extraction and conventional laparoscopic surgery with mini-laparotomy in the treatment of ascending colon cancer (with video) - 17/08/21
Abstract |
Background and Aims |
Now that the debate about the safety and effectiveness of laparoscopic versus open surgery is over, attention has turned to innovations that can verify whether minimizing the impact of laparoscopy on the abdominal wall can further reduce pain, improve patient comfort, lead to superior cosmesis, and reduce morbidity. The aim of this study was to further explore the application value of totally laparoscopic right hemicolectomy with transcolonic natural orifice specimen extraction (NOSE) and to evaluate the short-term efficacy of transcolonic NOSE surgery for resecting specimens of ascending colon cancer.
Methods |
From January 2016 to May 2017, a retrospective study was conducted in Guangxi. Propensity score matching was used to minimize the bias from nonrandomized treatment assignment. Patients were followed up through May 2020.
Results |
Forty-nine patients underwent totally laparoscopic right hemicolectomy with transcolonic NOSE and 116 patients laparoscopic right hemicolectomy with mini-laparotomy (ML) procedures at our institution. After propensity score matching, each group included 45 patients, and all covariate imbalances were alleviated. The transcolonic NOSE group and the ML group did not differ significantly in terms of baseline clinical characteristics. The transcolonic NOSE group was associated with a shorter time to first flatus (NOSE vs ML: 1.8 ± .5 vs 3.2 ± .8, P = .032), a shorter length of hospital stay (11.3 ± 2.5 days vs 13.0 ± 3.1 days, P = .034), a shorter time to first liquid intake (2.6 ± .8 vs 3.8 ± .9, P = .068), less pain (1.8 ± .8 vs 4.2 ± .7, P = .013), less analgesia requirement (6 [13.3%] vs 21 [46.7%], P = .001), and lower C-reactive protein levels on postoperative day 1 (3.6 ± 1.7 vs 8.2 ± 2.2, P = .001) and postoperative day 3 (NOSE 2.4 ± 1.4 vs M: 4.6 ± 1.7 [P = .013]) than the ML group. The median follow-up was 28.4 months (interquartile range, 18.0-36.0). The 3-year overall survival rates were similar between the transcolonic NOSE group and the ML group.
Conclusions |
In total, laparoscopic right hemicolectomy with transcolonic specimen extraction appears to be safe for selected patients with ascending colon cancer as a minimally invasive surgery.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Abbreviations : BMI, ML, NOSE, POD, PSM
Plan
| DISCLOSURE: All authors disclosed no financial relationships. Research support for this study was provided by grants from the Scientific Research Project of Guangxi Health Commission (grant nos. Z20180739 and Z20180713) and the Youth Foundation of People’s Hospital of Guangxi Zhuang Autonomous Region (grant no. QN2018-22). |
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| If you would like to chat with an author of this article, you may contact Dr Kong at kfb.32@163.com. |
Vol 94 - N° 3
P. 642-650 - septembre 2021 Retour au numéro
Article précédent
- Continuing Medical Education Exam: September 2021
- Karthik Ravi, William Ross, Ara Sahakian, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace
- Natural orifice specimen extraction for colorectal cancer removal: the best of both worlds
- Shyam Thakkar, Anisha Pancholi, Neil Carleton
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