Computational Fluid Dynamic Modeling Reveals Nonlinear Airway Stress during Trachea Development - 23/10/21
Doi : 10.1016/j.jpeds.2021.07.038
Eric C. Mason, MD 1, Zhenxing Wu, PhD 1, Sam McGhee, BS 1, Jennifer Markley, BS 1, Maria Koenigs, MD 1, Amanda Onwuka, PhD, MPH 2, Tendy Chiang, MD 1, 3, 4, Kai Zhao, PhD 1, ⁎ 
1 Department of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH
2 Center for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH
3 Department of Otolaryngology, Nationwide Children's Hospital, Columbus, OH
4 Center for Regenerative Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, OH
∗Reprint requests: Kai Zhao, PhD, Department of Otolaryngology–Head and Neck Surgery, The Ohio State University, 951 Olentangy River Rd, Columbus, OH 43212.Department of Otolaryngology–Head and Neck SurgeryThe Ohio State University951 Olentangy River RdColumbusOH43212
Abstract |
Normative trachea dimensions and aerodynamic information during development was collected to establish clinical benchmarks and showed that airway development seems to outpace respiratory demands. Infants and toddlers' trachea exhibit higher aerodynamic stress that significantly decreases by teenage years. This implies large airway pathology in younger children may have a more substantial clinical impact.
Le texte complet de cet article est disponible en PDF.Keywords : airflow metrics, airway modeling, pediatric airway physiology
Abbreviations : CFD, CT, PFV, WSS
Plan
| Supported by Nationwide Children's Hospital (the Clinical and Translational Intramural Funding Program [to E.M.]); National Institutes of Health National Heart, Lung, and Blood Institute (K08 HL138460 [to T.C.]; and National Institutes of Health National Institute on Deafness and Other Communication (R01 DC013626 [to K.Z.] and R21 DC017530 [to K.Z.]). The authors declare no conflicts of interest. |
© 2021
Elsevier Inc. Tous droits réservés.
Vol 238
P. 324 - novembre 2021 Retour au numéro
Article précédent
- Recurrence of Acute Myocarditis Temporally Associated with Receipt of the mRNA Coronavirus Disease 2019 (COVID-19) Vaccine in a Male Adolescent
- Prashant K. Minocha, Donna Better, Rakesh K. Singh, Tasneem Hoque
- Siblings with Thickened Palms and Soles
- Henrietta Albela, Kin Fon Leong
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?