Acute ischemic stroke (AIS) is rare in children, and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported.
We two patients with AIS presenting with large vessel occlusive disease in previously healthy adolescents recently exposed to SARS-CoV-2 infection.
Both patients were subsequently diagnosed with and treated for MIS-C. Here, we discuss the course of their treatments and clinical responses.
Early recognition and diagnosis of AIS with large vessel occlusion in children with MIS-C is critical to make available all treatment options to improve clinical outcomes.Le texte complet de cet article est disponible en PDF.
Keywords : Stroke, COVID-19, MIS-C, Acute ischemic infarction, Large vessel, SARS-Cov2
| Funding: This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
| Conflict of interest: None.
| Author contributions: Jaimie Chang and Zachary Bulwa provided substantial contributions to the conception and design of the work, the acquisition, analysis, and interpretation of the data. Jaimie Chang, Zachary Bulwa, and Rima Dafer were responsible for the drafting of the manuscript. All authors were responsible for revising the manuscript. All authors were responsible for patient care. All authors give final approval of the version to be published and are in agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy and integrity of the work is appropriate.
| Data sharing: Deidentified data are available upon request.