Editorial: Second-Generation Antipsychotics for Bipolar Depression in Youths: The Best Evidence Synthesis Is a Strong Call for Further Evidence - 20/01/22
, Jean A. Frazier, MD b, Cinzia Del Giovane, PhD cRésumé |
Before the network meta-analysis (NMA) by DelBello et al. in this issue of the Journal, no NMA had been published on the pharmacological treatment of bipolar depression in youths. DelBello et al. have filled this gap by conducting the first NMA of second-generation antipsychotics for major depressive episodes in youths with bipolar disorder. The NMA by DelBello et al. is arguably the best available evidence synthesis on the comparative efficacy and safety of second-generation antipsychotics for bipolar depression in youths. However, it should be considered as the first building block that strongly calls for more evidence to support clinical decision making in the management of this serious but overlooked condition.
Le texte complet de cet article est disponible en PDF.| The authors have reported no funding for this work. |
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| Author Contributions Writing – original draft: Cortese Writing – review and editing: Cortese, Frazier, Del Giovane |
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| Disclosure: Dr. Cortese has served as deputy editor of Evidence-Based Mental Health, associate editor of Child and Adolescent Mental Health, and on the editorial boards of the Journal of Child Psychology and Psychiatry, the Journal of Child and Adolescent Psychopharmacology, and CNS Drugs. He has received honoraria from the Association for Child and Adolescent Mental Health, the British Association for Psychopharmacology, Healthcare Convention, and the Canadian ADHD Resource Alliance. Dr. Frazier has received grant or research support from the National Institute of Mental Health, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Fulcrum Therapeutics, and Roche. She has served on the editorial board of the Harvard Review of Psychiatry and as associate editor of the Journal of Child and Adolescent Psychopharmacology. Dr. Del Giovane has reported no biomedical financial interests or potential conflicts of interest. |
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| All statements expressed in this column are those of the authors and do not reflect the opinions of the Journal of the American Academy of Child and Adolescent Psychiatry. See the Guide for Authors for information about the preparation and submission of Editorials. |
Vol 61 - N° 2
P. 128-130 - février 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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