Liposuction is the most common procedure in plastic surgery and becoming increasingly common in male patients. Recently, liposuction has evolved from a procedure whose goal was primarily fat extraction, to one that sculpts tissue with the goal of enhancing muscular definition. The popularity of high-definition liposuction has increased rapidly due to visibility on social media and has broadened the patient population presenting for liposuction, particularly among men. Herein, the authors review patient selection, surgical technique, and postoperative outcomes following high-definition liposuction in male patients.