Cold versus hot snare resection with or without submucosal injection of 6- to 15-mm colorectal polyps: a randomized controlled trial - 14/07/22
Abstract |
Background and Aims |
Cold snare resection of colorectal lesions has been found to be safe and effective for an expanding set of colorectal lesions. In this study, we sought to understand the efficacy of simple cold snare resection and cold EMR versus hot snare resection and hot EMR for colorectal lesions 6 to 15 mm in size.
Methods |
At 3 U.S. centers, 235 patients with 286 colorectal lesions 6 to 15 mm in size were randomized to cold snaring, cold EMR, hot snaring, or hot EMR for nonpedunculated colorectal lesions 6 to 15 mm in size. The primary outcome was complete resection determined by 4 biopsy samples from the defect margin and 1 biopsy sample from the center of the resection defect.
Results |
The overall incomplete resection rate was 2.4% (95% confidence interval [CI], .8%-7.5%). All 7 incompletely removed polyps were 10 to 15 mm in size and removed by hot EMR (n = 4, 6.2%), hot snare (n = 2, 2.2%), or cold EMR (n = 1, 1.8%). Cold snaring had no incomplete resections, required less procedural time than the other methods, and was not associated with serious adverse events.
Conclusions |
Cold snaring is a dominant resection technique for nonpedunculated colorectal lesions 6 to 15 mm in size. (Clinical trial registration number: NCT03462706.)
Le texte complet de cet article est disponible en PDF.Abbreviations : ITT, VAMC, WRJ
Plan
| DISCLOSURE: The following authors disclosed financial relationships: D. K Rex: Consultant for Olympus Corporation, Boston Scientific, Aries Pharmaceutical, Braintree Laboratories, Norgine, Endokey, GI Supply, and Medtronic; research support from Olympus Corporation, Medivators, Erbe USA Inc, and Braintree Laboratories; shareholder in Satisfai Health. Krishna C. Vemulapalli: Employee of Cook Research Incorporated, a Cook Group company. All other authors disclosed no financial relationships. |
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| See CME section, p. 373. |
Vol 96 - N° 2
P. 330-338 - août 2022 Retour au numéro
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