Prostate Cancer : Update on Grading and Reporting - 05/11/22
, Jonathan Epstein, MD a, b, c, ⁎ 
Abstract |
The Gleason scoring system and Grade Group systems facilitate accurate grading and reporting of prostate cancer, which are essential tasks for surgical pathologists. Gleason Pattern 4 is critical to recognize because it signifies a risk for more aggressive behavior than Gleason Pattern 3 carcinoma. Prostatic adenocarcinoma with radiation or androgen therapy effect, with aberrant P63 expression, or with Paneth cell–like differentiation represent pitfalls in prostate cancer grading because although they display architecture associated with aggressive behavior in usual prostatic adenocarcinoma, they do not behave aggressively and using conventional Gleason scoring in these tumors would significantly overstate their biologic potential.
Le texte complet de cet article est disponible en PDF.Keywords : Prostate cancer, Gleason scoring, Grade groups, Intraductal carcinoma, Prostatic adenocarcinoma with aberrant P63 expression, Prostatic adenocarcinoma with Paneth cell–like differentiation
Plan
Vol 15 - N° 4
P. 579-589 - décembre 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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