Vitrectomy Improves Contrast Sensitivity in Multifocal Pseudophakia With Vision Degrading Myodesopsia - 25/11/22
Highlights |
• | Vision degrading myodesopsia (VDM) is characterized by abnormally increased vitreous density and impaired contrast sensitivity. |
• | Patients with VDM and multifocals IOLs have worse contrast sensitivity than phakics and monofocal IOLs. |
• | Vitrectomy improves vision in all cases, including multifocal intraocular lenses. |
Résumé |
PURPOSE |
Multifocal intraocular lenses (MFIOL) are associated with degradation in contrast sensitivity function (CSF); yet the contribution of vitreous is not known, nor is the benefit of vitrectomy.
DESIGN |
Prospective, nonrandomized clinical study.
METHODS |
A total of 180 eyes of 180 patients (55 MFIOL, 60 monofocal intraocular lenses [MIOL], 65 phakic) with symptomatic vitreous opacities were enrolled. Vitreous structure was assessed with quantitative ultrasonography (QUS). Vision was evaluated with visual acuity and CSF measurements.
RESULTS |
Vitreous echodensity was the same in all lens cohorts, yet CSF was worse in MFIOL eyes (P < .001). In 86 patients who elected vitrectomy, there was 68% greater vitreous echodensity and 31% worse CSF than in observation controls (P < .0001 for each). Preoperatively, CSF was 25% worse in MFIOL than in MIOL (P = .014). Postoperatively, vitreous echodensity decreased by 55%, 51%, and 52%, whereas CSF improved by 37% 48% in and 43% in MFIOL, MIOL, and phakic eyes, respectively (P < .0001 for each). NEI Visual Function Questionnaire analyses showed improved visual well-being.
CONCLUSIONS |
Patients with vision degrading myodesopsia who elected vitrectomy had greater vitreous echodensity and worse CSF than controls, but no other differences in age, sex, or myopia. MFIOL eyes had worse CSF than MIOL and phakic eyes, very possibly due to combined effects of the MFIOL and vitreous opacification. Limited vitrectomy reduced vitreous echodensity and improved CSF in all eyes. All patients with CSF-degrading vitreous opacities benefited from limited vitrectomy, including those with MFIOL. As MFIOL eyes had 37% improvement in CSF, patients with MFIOL and vision degrading myodesopsia merit consideration of vitrectomy.
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| Supplemental Material available at AJO.com. |
|
| Parts of the data in the manuscript were previously presented at ARVO 2018, the American Society of Retinal Specialists 2021, and the American Society of Cataract and Refractive Surgery 2022. |
Vol 244
P. 196-204 - décembre 2022 Retour au numéro
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