Minimum wall shear stress points and their underlying intra-aneurysmal flow structures of unruptured cerebral aneurysms on 4D flow MRI - 20/04/23
Highlights |
• | This study first identified minimum wall shear stress (Min-WSS) points and their underlying intra-aneurysmal flow structure patterns in unruptured cerebral aneurysms using four-dimensional flow magnetic resonance imaging. |
• | The location of Min-WSS point corresponded with the location of the vortex core or center in 76% of all aneurysms. |
• | The Min-WSS points were located not only on the apex, but also on the neck. |
• | The location of the Min-WSS point and underlying intra-aneurysmal flow structure affected the Min-WSS value. |
Abstract |
Background and purpose |
Minimum wall shear stress (Min-WSS) points may be associated with wall instability of unruptured cerebral aneurysms. We aimed to investigate the relationship between the locations of Min-WSS points and their underlying intra-aneurysmal flow structure patterns in unruptured cerebral aneurysms using four-dimensional (4D) flow magnetic resonance imaging (MRI).
Materials and methods |
Min-WSS points and the intra-aneurysmal flow structure patterns were identified in 50 unruptured aneurysms by 4D flow MRI.
Results |
The Min-WSS points were located around a vortex core tip in 31 (62.0%) aneurysms and on an intra-bleb vortex center in 7 (14.0%). Sixteen (32.0%) aneurysms had the Min-WSS points on the aneurysmal apex, and in 24 (48.0%) were on the neck. The Min-WSS values of aneurysms with the Min-WSS points on an intra-bleb flow were significantly lower than those of the other groups (P = 0.030). Aneurysms with the Min-WSS points on the neck had significantly higher Min-WSS values than the other aneurysms (P = 0.008).
Conclusions |
The location of the Min-WSS point was corresponding to the vortex core or center in 76% of all aneurysms. The underlying intra-aneurysmal flow structure and location of the Min-WSS point affect the Min-WSS value. Further studies are needed to characterize Min-WSS points to identify aneurysms with a higher risk of wall instability.
Le texte complet de cet article est disponible en PDF.Keywords : Wall instability, Unruptured cerebral aneurysm, Wall shear stress, Vortex, 4D flow MRI
Abbreviation : CFD, 4D, MRI, Min-WSS, WSS
Plan
Vol 50 - N° 3
P. 302-308 - mai 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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