Characteristics of people with optimally-managed type 1 diabetes - 11/06/23
, Richard IG Holt b, cAbstract |
Objective |
The aim is to describe the characteristics of people with type 1 diabetes who are meeting all seven glycemic targets set by international consensus.
Research Design & Methods |
We analyzed continuous glucose monitoring (CGM) data from 497 participants (aged 18-70 yrs). Time-in-range, time above and below range, co-efficient of variability, and glucose management indicator (GMI) were combined with demographic data, insulin delivery, and exercise.
Results |
While 68% of participants achieved a GMI below 7% (53 mmol/mol), 39% met all seven glycemic targets. Older people and those of White ethnicity were more likely to meet these targets. Men and women were equally likely to meet all targets, although men were more likely to experience hypoglycemia while women were more likely to experience hyperglycemia. Hybrid-closed loop (HCL) system users were more likely to meet all targets than people using a standard pump or multiple daily injections.
Conclusions |
Only 56% of those with a GMI below 7% (53 mmol/mol) met all seven targets, illustrating how glycemic management involves more than GMI/HbA1c lowering alone, which has implications for estimates of optimally managed participants in the wider population of people with type 1 diabetes. Demographic inequalities were prevalent. Using a HCL system clearly facilitated the achievement of glycemic targets.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | Optimal management of type 1 diabetes can been defined by seven criteria, as recommended in the ADA and EASD consensus report on the management of type 1 diabetes in adults. We studied the percentage and the characteristics of adults with diabetes who met these criteria. |
• | Older people and people identifying as White were more likely to meet all seven glycemic targets. |
• | Women across all age groups spent less time in range and spent more time above range than men, whereas men spent more time below range. |
• | Hybrid-closed loop insulin delivery systems were a powerful predictor of meeting all seven glycemic targets |
Keywords : Adult, Self-management, CGM, Hybrid closed loop, Age, Inequality
Abbreviations : CGM, eAG, GMI, HCL, MDI, TIR
Plan
Vol 12
Article 100153- octobre 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
