Physical urticaria: Clinical features, pathogenesis, diagnostic work-up, and management - 15/07/23

, Evangelos A.A. Christou, MD, PgCert, MedEd, MRCP (UK) a, Marcus Maurer, MD b, c, Clive E. Grattan, MA, MD a, Christos Tziotzios, MA, MPhil, MB, BChir (Cantab), PhD a, John A. McGrath, MD aAbstract |
Physical urticaria is a type of urticaria in which recurrent wheals and/or angioedema occur following exposure of the skin to a physical stimulus. It is classified according to its triggers, which may be mechanical (friction, pressure, and vibration), thermal (cold and heat), or solar electromagnetic radiation. Symptoms of different physical urticarias can develop following specific activities that expose patients to an eliciting stimulus and may be variably accompanied by mucosal involvement and systemic symptoms, including nausea, headache, or even anaphylaxis. Differentiation of physical urticaria from other chronic urticarias requires careful clinical assessment and confirmatory provocation testing, which in turn can inform appropriate management. This clinical review provides an evidence-based summary of the epidemiology, clinical features, pathogenesis, diagnostic work-up, and management of physical urticaria.
Le texte complet de cet article est disponible en PDF.Key words : angioedema, evidence-based dermatology, itch, mast cell, urticaria, wheals
Abbreviations used : AH-1, ColdU, CU, CSU, DPU, HU, IgE, PROM, PU, RCT, SD, SU, VA
Plan
| Funding sources: S.M.M. is currently supported by a Medical Research Council Clinical Research Training Fellowship (MR/V006746/1). |
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| IRB approval status: Not applicable. |
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| Patient consent on file: Consent for the publication of recognizable patient photographs or other identifiable material was obtained by the authors and included at the time of article submission to the journal stating that all patients gave consent with the understanding that this information will be publicly available. |
Vol 89 - N° 2
P. 324-337 - août 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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